Fluorescence enhanced lab-on-a-chip patterned using a hybrid technique of femtosecond laser direct writing and anodized aluminum oxide porous nanostructuring
文献类型：期刊论文
| 作者 | Z.Yu; Y.Lei; W.Yu; J.Cheng; J.Xing; X.Zheng; Z.Zhan; B.Wang |
| 刊名 | Nanoscale Advances
 |
| 出版日期 | 2019 |
| 卷号 | 1期号:9页码:3474-3484 |
| 关键词 | Aluminum oxide,Alumina,Chemical modification,Electrochemical deposition,Energy transfer,Femtosecond lasers,Fluorescence,Hydrophilicity,Lab-on-a-chip,Laser excitation,Molecules,Photoresists,Reduction,Rhodium compounds,Spectral resolution,Superhydrophobicity |
| ISSN号 | 25160230 |
| DOI | 10.1039/c9na00352e |
| 英文摘要 | In this paper, we demonstrate a simple yet effective hybrid method to fabricate lab-on-a-chip devices on aluminum (Al) foil. Instead of using conventional photoresists and lithography methods, an array of square units is first produced by femtosecond laser direct writing, followed by generating highly ordered anodized aluminum oxide (AAO) nanoporous structures within each unit. The AAO treated area becomes hydrophilic. Next, we functionalize the surrounding area outside the square units to superhydrophobic by electrochemical deposition and further chemical modification. This hydrophilic and hydrophobic pattern allows us to confine the liquid samples to be detected within the hydrophilic AAO detection area. We use rhodamine 6G (R6G) as a probe, and obtain a fluorescence intensity enhancement from R6G by 70 times over a flat surface. This leads to the detection sensitivity of R6G molecules to a concentration as low as 10-17 mol L-1. By mixing R6G with RhB molecules, the fluorescence emission bands shift significantly due to the addition of RhB molecules, showing a significantly improved spectral resolution compared to traditional fluorescence spectrometers for liquid samples. This phenomenon can be attributed to the energy transfer between R6G and RhB under laser excitation, which was enhanced by the AAO nanostructures. The array-based LOC device demonstrated in this paper is simple and convenient to fabricate, has low sample consumption and dramatically enhances the fluorescence yield with improved spectral resolution. 2019 The Royal Society of Chemistry. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.ciomp.ac.cn/handle/181722/62844]  |
| 专题 | 中国科学院长春光学精密机械与物理研究所 |
| 推荐引用方式 GB/T 7714 | Z.Yu,Y.Lei,W.Yu,et al. Fluorescence enhanced lab-on-a-chip patterned using a hybrid technique of femtosecond laser direct writing and anodized aluminum oxide porous nanostructuring[J]. Nanoscale Advances,2019,1(9):3474-3484. |
| APA | Z.Yu.,Y.Lei.,W.Yu.,J.Cheng.,J.Xing.,...&B.Wang.(2019).Fluorescence enhanced lab-on-a-chip patterned using a hybrid technique of femtosecond laser direct writing and anodized aluminum oxide porous nanostructuring.Nanoscale Advances,1(9),3474-3484. |
| MLA | Z.Yu,et al."Fluorescence enhanced lab-on-a-chip patterned using a hybrid technique of femtosecond laser direct writing and anodized aluminum oxide porous nanostructuring".Nanoscale Advances 1.9(2019):3474-3484. |
入库方式： OAI收割
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。