中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Active-modulated, random-illumination, super-resolution optical fluctuation imaging

文献类型:期刊论文

作者B. J. Wang, Z. J. Liu, L. Zhou, Y. Y. Fei, C. L. Yang, L. Mi, Q. Q. Mu and J. Ma
刊名Nanoscale
出版日期2020
卷号12期号:32页码:16864-16874
ISSN号2040-3364
DOI10.1039/d0nr03255g
英文摘要Super-resolution optical fluctuation imaging (SOFI) provides subdiffraction resolution based on the analysis of temporal stochastic intensity fluctuations. However, conventional SOFI imaging relies on the intrinsic blinking properties of fluorescent markers and suffers from severe artifacts and signal losses owing to the unmatched blinking on-time ratio. Herein, we propose active-modulated, random-illumination, super-resolution optical fluctuation imaging that allows the traditional SOFI to overcome the effect of the intrinsic impertinent blinking characteristic of fluorescent markers. We demonstrate theoretically and experimentally that this method of active-modulated random illumination can generate random illumination patterns with a controllable blinking on-time ratio to match the high-order SOFI reconstruction considerably reducing the generated artifacts and signal losses. High-order, high-quality images can be obtained with increased lateral resolution.
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语种英语
源URL[http://ir.ciomp.ac.cn/handle/181722/64286]  
专题中国科学院长春光学精密机械与物理研究所
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GB/T 7714
B. J. Wang, Z. J. Liu, L. Zhou, Y. Y. Fei, C. L. Yang, L. Mi, Q. Q. Mu and J. Ma. Active-modulated, random-illumination, super-resolution optical fluctuation imaging[J]. Nanoscale,2020,12(32):16864-16874.
APA B. J. Wang, Z. J. Liu, L. Zhou, Y. Y. Fei, C. L. Yang, L. Mi, Q. Q. Mu and J. Ma.(2020).Active-modulated, random-illumination, super-resolution optical fluctuation imaging.Nanoscale,12(32),16864-16874.
MLA B. J. Wang, Z. J. Liu, L. Zhou, Y. Y. Fei, C. L. Yang, L. Mi, Q. Q. Mu and J. Ma."Active-modulated, random-illumination, super-resolution optical fluctuation imaging".Nanoscale 12.32(2020):16864-16874.

入库方式: OAI收割

来源:长春光学精密机械与物理研究所

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