Role of manganese superoxide dismutase (Mn-SOD) against Cr(III)-induced toxicity in bacteria
文献类型：期刊论文
| 作者 | Niu, Aping2,3 ; Bian, Wan-Ping2; Feng, Shuang-Long2; Pu, Shi-Ya1,2; Wei, Xing-Yi2,5; Yang, Yi-Fan2,4; Song, Li-Yan2; Pei, De-Sheng1,2,4
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| 刊名 | JOURNAL OF HAZARDOUS MATERIALS
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| 出版日期 | 2021-02-05 |
| 卷号 | 403页码:10 |
| ISSN号 | 0304-3894 |
| 关键词 | Oxidative stress Mn-SOD Morphology variation Cell division Cr species |
| DOI | 10.1016/j.jhazmat.2020.123604 |
| 通讯作者 | Pei, De-Sheng(peids@cigit.ac.cn) |
| 英文摘要 | The toxicity of Cr(VI) was widely investigated, but the defense mechanism against Cr(III) in bacteria are seldom reported. Here, we found that Cr(III) inhibited bacterial growth and induced reactive oxygen species (ROS). After exposure to Cr(III), loss of sodA not only led to the excessive generation of ROS, but also enhanced the level of lipid peroxidation and reduced the GSH level, indicating that the deficiency of Mn-SOD decreased the bacterial resistance ability against Cr(III). The adverse effects of oxidative stress caused by Cr(III) could be recovered by the rescue of Mn-SOD in the sodA-deficient strain. Besides the oxidative stress, Cr(III) could cause the bacterial morphology variation, which was distinct between the wild-type and the sodA-deficient strains due to the differential expressions of Z-ring division genes. Moreover, Mn-SOD might prevent Cr(III) from oxidation on the bacterial surface by combining with Cr(III). Taken together, our results indicated that the Mn-SOD played a vital role in regulating the stress resistance, expression of cell division-related genes, bacterial morphology, and chemistry valence state of Cr. Our findings firstly provided a more in-depth understanding of Cr(III) toxicity and bacterial defense mechanism against Cr(III). |
| 资助项目 | CAS Team Project of the Belt and Road ; Three Hundred Leading Talents in Scientific and Technological Innovation Program of Chongqing[CSTCCXLJRC201714] ; National Natural Science Foundation of China[51641907] ; Chongqing Science and Technology Commission[cstc2019jcyj-zdxmX0035] ; Chongqing Science and Technology Commission[cstc2019jcyjmsxm1824] ; Chongqing Science and Technology Commission[2019-04] ; Program of China-Sri Lanka Joint Center for Water Technology Research and Demonstration by the Chinese Academy of Sciences (CAS)/China-Sri Lanka Joint Center for Education and Research by the CAS |
| WOS研究方向 | Engineering ; Environmental Sciences & Ecology |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| WOS记录号 | WOS:000596474900003 |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/12676]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | Pei, De-Sheng |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Key Lab Reservoir Aquat Environm, Chongqing 400714, Peoples R China 3.Guizhou Univ, Coll Resources & Environm Engn, Guiyang 550025, Guizhou, Peoples R China 4.Henan Normal Univ, Coll Life Sci, Xinxiang 453007, Henan, Peoples R China 5.Chongqing Jiaotong Univ, Sch River & Ocean Engn, Chongqing 400074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Niu, Aping,Bian, Wan-Ping,Feng, Shuang-Long,et al. Role of manganese superoxide dismutase (Mn-SOD) against Cr(III)-induced toxicity in bacteria[J]. JOURNAL OF HAZARDOUS MATERIALS,2021,403:10. |
| APA | Niu, Aping.,Bian, Wan-Ping.,Feng, Shuang-Long.,Pu, Shi-Ya.,Wei, Xing-Yi.,...&Pei, De-Sheng.(2021).Role of manganese superoxide dismutase (Mn-SOD) against Cr(III)-induced toxicity in bacteria.JOURNAL OF HAZARDOUS MATERIALS,403,10. |
| MLA | Niu, Aping,et al."Role of manganese superoxide dismutase (Mn-SOD) against Cr(III)-induced toxicity in bacteria".JOURNAL OF HAZARDOUS MATERIALS 403(2021):10. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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