Terahertz detection of porosity and porous microstructure in pharmaceutical tablets: A review
文献类型：期刊论文
| 作者 | Lu, Xingxing2; Sun, Huihui2; Chang, Tianying2,3; Zhang, Jin2; Cui, Hong-Liang1,2
|
| 刊名 | INTERNATIONAL JOURNAL OF PHARMACEUTICS
 |
| 出版日期 | 2020-12-15 |
| 卷号 | 591页码:10 |
| 关键词 | Pharmaceutical tablets THz technology Porosity Porous microstructure |
| ISSN号 | 0378-5173 |
| DOI | 10.1016/j.ijpharm.2020.120006 |
| 通讯作者 | Zhang, Jin() |
| 英文摘要 | Pores are inevitably produced during the production of pharmaceutical tablets, which greatly affects a range of tablet properties such as hardness, friability, tensile strength, disintegration, dissolution, and ultimately the bioavailability of an orally administered tablet. The pursuit of speed and non-destructiveness in detection of pores in pharmaceutical tablets has recently ushered in the use of terahertz (THz) techniques. This review briefly introduces the mechanism of the formation of the pores in tablets and the traditional methods of detecting them. The main focus is the relevant research work of THz technology applied to the detection of the pores in tablets, including the quantitative detection of porosity and analysis of porous microstructure. It also discusses the challenges and the future development directions of THz technology in the detection of pores in tablets. |
| 资助项目 | National Natural Science Foundation of China[61705120] ; National Natural Science Foundation of China[61875196] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000600735200039 |
| 出版者 | ELSEVIER |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/12688]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | Zhang, Jin |
| 作者单位 | 1.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China 2.Jilin Univ, Coll Instrumentat & Elect Engn, Changchun 130061, Jilin, Peoples R China 3.Qilu Univ Technol, Inst Automat, Shandong Acad Sci, Jinan 250014, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lu, Xingxing,Sun, Huihui,Chang, Tianying,et al. Terahertz detection of porosity and porous microstructure in pharmaceutical tablets: A review[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS,2020,591:10. |
| APA | Lu, Xingxing,Sun, Huihui,Chang, Tianying,Zhang, Jin,&Cui, Hong-Liang.(2020).Terahertz detection of porosity and porous microstructure in pharmaceutical tablets: A review.INTERNATIONAL JOURNAL OF PHARMACEUTICS,591,10. |
| MLA | Lu, Xingxing,et al."Terahertz detection of porosity and porous microstructure in pharmaceutical tablets: A review".INTERNATIONAL JOURNAL OF PHARMACEUTICS 591(2020):10. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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