Influence of pH on aptamer-based gold nanoparticles colorimetric sensors
文献类型：期刊论文
| 作者 | Li, Jiye3,4; Zuo, Xinyu1,4,5; Liu, Hao2; Xie, Yuanyang3,4; Huang, Yu3,4
|
| 刊名 | JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
 |
| 出版日期 | 2021-01-30 |
| 页码 | 9 |
| 关键词 | Aptamer Gold nanoparticles Colorimetric pH |
| ISSN号 | 1735-207X |
| DOI | 10.1007/s13738-021-02182-3 |
| 通讯作者 | Xie, Yuanyang(yuanyangxie@outlook.com) ; Huang, Yu(huangyu@cigit.ac.cn) |
| 英文摘要 | In recent years, aptamer-based gold nanoparticles (AuNPs) colorimetric sensors have received extensive attention, especially in discovery of disease markers and food safety. However, the detection sensitivity is not high enough and the detection results are prone to false positives. Therefore, it is urgently to improve the performance of sensors, ranging from the optimization of sensor detection conditions and establishment of new sensing methods. pH is an important parameter in the solution. In this article, pH was employed to adjust the aptamer charge to increase the sensitivity of lysozyme detection, and the detection limit can be approached as low as 0.05 nM. pH was also used to adjust the target charge to improve the performance of sensors. Chloramphenicol (CAP) and precursors of chloramphenicol (CAP-base) were used as targets to verify the charge effect introduced by pH adjustment. The experiment found that the neutral or electronegativity target would weaken the response of the sensor. To achieve the detection of CAP (electron neutral), a competitive colorimetric sensor had been successfully established to detect CAP. The Derjaguin-Landau-Verwey-Overbeck (DLVO) theory was used to explain the effect of pH on sensor performance. Therefore, by adjusting pH, the detection sensitivity can be improved significantly and a new sensing method can be established, which provide a broad application prospects for chemical, environmental and biological sensing. |
| 资助项目 | Natural Science Foundation of Chongqing[cstc2018jcyjAX0718] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000612896800001 |
| 出版者 | SPRINGER |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/12828]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | Xie, Yuanyang; Huang, Yu |
| 作者单位 | 1.Chongqing Univ, Chongqing 400044, Peoples R China 2.Chongqing Survey Inst, 6 Dazhulin Eastern Rd, Chongqing 401121, Peoples R China 3.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Upper Changjiang River Bur Hydrol & Water Resourc, 410 Haier Rd, Chongqing 400021, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Jiye,Zuo, Xinyu,Liu, Hao,et al. Influence of pH on aptamer-based gold nanoparticles colorimetric sensors[J]. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY,2021:9. |
| APA | Li, Jiye,Zuo, Xinyu,Liu, Hao,Xie, Yuanyang,&Huang, Yu.(2021).Influence of pH on aptamer-based gold nanoparticles colorimetric sensors.JOURNAL OF THE IRANIAN CHEMICAL SOCIETY,9. |
| MLA | Li, Jiye,et al."Influence of pH on aptamer-based gold nanoparticles colorimetric sensors".JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2021):9. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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