Study on an artificial phenomenon observed in terahertz biological imaging
文献类型：期刊论文
| 作者 | Yang, Zhongbo1,3,4 ; Zhang, Muyang5; Li, Dandan3,4; Chen, Ligang3,4; Fu, Ailing2; Liang, Yanmei5; Wang, Huabin1,3,4
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| 刊名 | BIOMEDICAL OPTICS EXPRESS
 |
| 出版日期 | 2021-06-01 |
| 卷号 | 12期号:6页码:3133-3141 |
| ISSN号 | 2156-7085 |
| DOI | 10.1364/BOE.424445 |
| 通讯作者 | Liang, Yanmei(ymliang@nankai.edu.cn) |
| 英文摘要 | Terahertz (THz) wave-based imaging of biological samples is an emerging but promising field. In the present work, we report an artificial phenomenon observed in imaging melanoma slices, which can lead to mistakenly interpretation of the experimental results. It was observed that a structure similar to but smaller than the sample contour appeared inside the melanoma slice image. The underlying mechanism of this phenomenon was then investigated both experimentally and theoretically. By imaging a regular standard sample (vinyl coverslip) with a THz time domain spectroscopy (THz-TDS) system and reconstructing its images at 0.8 and 1.2 THz, we can clearly observe the afore-mentioned artifacts. The experimental results are highly consistent with the simulations based on the Fresnel-Kirchhoff diffraction theory in which possible optical aberrations were incorporated. It can be concluded that this artifact was caused by the frequency-dependent diffraction of the sample edge. The work demonstrated here is essential for correct interpretation of the images obtained by the THz-TDS technique. (c) 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement |
| 资助项目 | Natural Science Foundation of Chongqing[cstc2018jcyjAX0405] ; Natural Science Foundation of Chongqing[cstc2019jcyjmsxmX0051] ; National Natural Science Foundation of China[61875092] ; National Natural Science Foundation of China[U1932132] ; University of Chinese Academy of Sciences Supported Program for Tackling Key Problems in Science and Technology[E029610601] ; National Key Research and Development Program of China[2017YFF0106303] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| WOS记录号 | WOS:000656913900006 |
| 出版者 | OPTICAL SOC AMER |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/13664]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | Liang, Yanmei |
| 作者单位 | 1.Univ Chinese Acad Sci, Chongqing Sch, Chongqing 400714, Peoples R China 2.Southwest Univ, Sch Pharmaceut Sci, Chongqing 400716, Peoples R China 3.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Ctr Appl Phys, Chongqing 400714, Peoples R China 4.Chinese Acad Sci, Chongqing Engn Res Ctr High Resolut & Three Dimen, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China 5.Nankai Univ, Inst Modern Opt, Tianjin 300350, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Zhongbo,Zhang, Muyang,Li, Dandan,et al. Study on an artificial phenomenon observed in terahertz biological imaging[J]. BIOMEDICAL OPTICS EXPRESS,2021,12(6):3133-3141. |
| APA | Yang, Zhongbo.,Zhang, Muyang.,Li, Dandan.,Chen, Ligang.,Fu, Ailing.,...&Wang, Huabin.(2021).Study on an artificial phenomenon observed in terahertz biological imaging.BIOMEDICAL OPTICS EXPRESS,12(6),3133-3141. |
| MLA | Yang, Zhongbo,et al."Study on an artificial phenomenon observed in terahertz biological imaging".BIOMEDICAL OPTICS EXPRESS 12.6(2021):3133-3141. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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