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Femtosecond laser-induced periodic grooves and nanopore clusters make a synergistic effect on osteogenic differentiation

文献类型：期刊论文

作者Xie, Haiqiong1,2; Zhang, Chenke2; Wang, Rui1; Tang, Hong2; Mu, Miduo2; Li, Huaisheng2; Guo, Yupeng2; Yang, Liang3; Tang, Kanglai2
刊名COLLOIDS AND SURFACES B-BIOINTERFACES
出版日期2021-12-01
卷号208页码:9
关键词Femtosecond laser Osteogenic differentiation Nanopore cluster Synergy Periodic groove
ISSN号0927-7765
DOI10.1016/j.colsurfb.2021.112021
通讯作者Yang, Liang(yangl@cigit.ac.cn) ; Tang, Kanglai(tangkanglai@hotmail.com)
英文摘要Polyether-ether-ketone (PEEK) materials have good biocompatibility, excellent corrosion resistance, chemical stability and an elastic modulus close to that of natural bone. However, due to its biological inertness, PEEK may affect osteogenic differentiation and leads to osseointegration failure, though PEEK is expected to improve osseointegration. In this work, by changing the power of femtosecond laser, micro-grooves are made on the PEEK surface. As observed by scanning electron microscopy, the trench has a periodic structure, the micro shape is neat, and the trench is also covered with nanometer-level pore clusters. In the in vitro culture experiments, through the proliferation experiment of mouse bone marrow mesenchymalstem cells (mBMSCs), cell viability analysis and alkaline phosphatase activity analysis, it is proven that after femtosecond laser treatment of the PEEK surface, the micro-grooves on the surface and the nanopore clusters due to laser energy ablation can produce a synergistic effect, enhancing the osteogenic differentiation ability of cells, and improving the bone integration ability of PEEK materials.
资助项目National Key Research and Development of China[2016YFC1100500] ; National NaturalScience Foundation of China[11702290]
WOS研究方向Biophysics ; Chemistry ; Materials Science
语种英语
WOS记录号WOS:000702868500008
出版者ELSEVIER
源URL[http://119.78.100.138/handle/2HOD01W0/14178]  
专题中国科学院重庆绿色智能技术研究院
通讯作者Yang, Liang; Tang, Kanglai
作者单位1.Chongqing Univ Posts & Telecommun, Sch Adv Mfg Engn, Chongqing 400065, Peoples R China
2.Army Med Univ Chinese PLA, Dept Orthoped, Sports Med Ctr, Affiliated Hosp 1, Chongqing 400038, Peoples R China
3.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China
推荐引用方式
GB/T 7714		 Xie, Haiqiong,Zhang, Chenke,Wang, Rui,et al. Femtosecond laser-induced periodic grooves and nanopore clusters make a synergistic effect on osteogenic differentiation[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2021,208:9.
APA Xie, Haiqiong.,Zhang, Chenke.,Wang, Rui.,Tang, Hong.,Mu, Miduo.,...&Tang, Kanglai.(2021).Femtosecond laser-induced periodic grooves and nanopore clusters make a synergistic effect on osteogenic differentiation.COLLOIDS AND SURFACES B-BIOINTERFACES,208,9.
MLA Xie, Haiqiong,et al."Femtosecond laser-induced periodic grooves and nanopore clusters make a synergistic effect on osteogenic differentiation".COLLOIDS AND SURFACES B-BIOINTERFACES 208(2021):9.

入库方式： OAI收割

来源：重庆绿色智能技术研究院

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