中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 重庆绿色智能技术研究院
  3. 中国科学院重庆绿色智能技术研究院
Nanopore Technology for the Application of Protein Detection

文献类型：期刊论文

作者Zeng, Xiaoqing1,4,5; Xiang, Yang1,4,5; Liu, Qianshan1,5; Wang, Liang1,5; Ma, Qianyun1,3,5; Ma, Wenhao1,4,5; Zeng, Delin1,2,5; Yin, Yajie1,5; Wang, Deqiang1,5
刊名NANOMATERIALS
出版日期2021-08-01
卷号11期号:8页码:16
关键词nanopore single-molecule detection protein detection solid-state nanopore
DOI10.3390/nano11081942
通讯作者Yin, Yajie(yinyajie@cigit.ac.cn) ; Wang, Deqiang(dqwang@cigit.ac.cn)
英文摘要Protein is an important component of all the cells and tissues of the human body and is the material basis of life. Its content, sequence, and spatial structure have a great impact on proteomics and human biology. It can reflect the important information of normal or pathophysiological processes and promote the development of new diagnoses and treatment methods. However, the current techniques of proteomics for protein analysis are limited by chemical modifications, large sample sizes, or cumbersome operations. Solving this problem requires overcoming huge challenges. Nanopore single molecule detection technology overcomes this shortcoming. As a new sensing technology, it has the advantages of no labeling, high sensitivity, fast detection speed, real-time monitoring, and simple operation. It is widely used in gene sequencing, detection of peptides and proteins, markers and microorganisms, and other biomolecules and metal ions. Therefore, based on the advantages of novel nanopore single-molecule detection technology, its application to protein sequence detection and structure recognition has also been proposed and developed. In this paper, the application of nanopore single-molecule detection technology in protein detection in recent years is reviewed, and its development prospect is investigated.
资助项目Chinese Academy of Sciences[Y52A100K10] ; National Nature Science Foundation of China[61471336] ; Joint-Scholar of West-Light Foundation of the Chinese Academy of Sciences
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种英语
WOS记录号WOS:000689865800001
出版者MDPI
源URL[http://119.78.100.138/handle/2HOD01W0/14227]  
专题中国科学院重庆绿色智能技术研究院
通讯作者Yin, Yajie; Wang, Deqiang
作者单位1.Univ Chinese Acad Sci, Chongqing Sch, Chongqing 400714, Peoples R China
2.Chongqing Univ Posts & Telecommun, Sch Optoelect Engn, Chongqing 400065, Peoples R China
3.Chongqing Univ Technol, Sch Pharm & Bioengn, Chongqing 400054, Peoples R China
4.Chongqing Univ, 174 Shazheng St, Chongqing 400044, Peoples R China
5.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China
推荐引用方式
GB/T 7714		 Zeng, Xiaoqing,Xiang, Yang,Liu, Qianshan,et al. Nanopore Technology for the Application of Protein Detection[J]. NANOMATERIALS,2021,11(8):16.
APA Zeng, Xiaoqing.,Xiang, Yang.,Liu, Qianshan.,Wang, Liang.,Ma, Qianyun.,...&Wang, Deqiang.(2021).Nanopore Technology for the Application of Protein Detection.NANOMATERIALS,11(8),16.
MLA Zeng, Xiaoqing,et al."Nanopore Technology for the Application of Protein Detection".NANOMATERIALS 11.8(2021):16.

入库方式： OAI收割

来源：重庆绿色智能技术研究院

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。