Direct optical observation of DNA clogging motions near controlled dielectric breakdown silicon nitride nanopores
文献类型：期刊论文
| 作者 | Xie, Wanyi1,2 ; Tian, Haibing1,2; Fang, Shaoxi1,2; Zhou, Daming1,2; Liang, Liyuan1,2; He, Shixuan1,2; Wang, Deqiang1,2
|
| 刊名 | SENSORS AND ACTUATORS B-CHEMICAL
 |
| 出版日期 | 2021-12-15 |
| 卷号 | 349页码:7 |
| 关键词 | Controlled dielectric breakdown (CBD) Solid-state nanopore DNA Motions Fluorescence |
| DOI | 10.1016/j.snb.2021.130796 |
| 通讯作者 | He, Shixuan(heshixuan@cigit.ac.cn) ; Wang, Deqiang(dqwang@cigit.ac.cn) |
| 英文摘要 | With the advantages of simple equipment and in-situ preparation of nanopores, the CBD method has been widely concerned by researchers. In this work, a fluorescence platform was set up to directly observe the lambda-DNA motions near the CBD prepared different kinds of SiNx nanopores. At first, for the one nanopore film, the lambda-DNA posttranslocation motion was observed. Then, for the multiple nanopores film, the current modulation phenomena of each nanopore after the DNA clogged the pores was observed. When the distance of asymmetric pores is less than the length of lambda-DNA, the larger nanopores are easy to be blocked preferentially by considering the tug-ofwar on lambda-DNA; when the asymmetric porous distance is larger than the DNA two polymer length, due to the forming a folded structure, the smaller nanopores are preferentially blocked. These results reveal that the clogging phenomena during the DNA translocation analysis for the nanopores are varied, and it should be considered for CBD-prepared nanopores. |
| 资助项目 | Natural Science Foundation of Chongqing, China[cstc2018jcyjAX0308] ; National Natural Science Foundation of China[41603089] |
| WOS研究方向 | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
| 语种 | 英语 |
| WOS记录号 | WOS:000707330900004 |
| 出版者 | ELSEVIER SCIENCE SA |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/14314]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | He, Shixuan; Wang, Deqiang |
| 作者单位 | 1.Univ Chinese Acad Sci, Chongqing Sch, Chongqing 400714, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xie, Wanyi,Tian, Haibing,Fang, Shaoxi,et al. Direct optical observation of DNA clogging motions near controlled dielectric breakdown silicon nitride nanopores[J]. SENSORS AND ACTUATORS B-CHEMICAL,2021,349:7. |
| APA | Xie, Wanyi.,Tian, Haibing.,Fang, Shaoxi.,Zhou, Daming.,Liang, Liyuan.,...&Wang, Deqiang.(2021).Direct optical observation of DNA clogging motions near controlled dielectric breakdown silicon nitride nanopores.SENSORS AND ACTUATORS B-CHEMICAL,349,7. |
| MLA | Xie, Wanyi,et al."Direct optical observation of DNA clogging motions near controlled dielectric breakdown silicon nitride nanopores".SENSORS AND ACTUATORS B-CHEMICAL 349(2021):7. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。