Red Fluorescent Emissive Gd-Phenolic Nanoparticles for In Vivo Fluorescence and Magnetic Resonance Bimodal Imaging
文献类型：期刊论文
| 作者 | Xu, Weibing2; Zhang, Jia2; Zhao, Minzhi2; Yang, Zhijie1; Wu, Qingfeng3 ; Nian, Fang2
|
| 刊名 | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
 |
| 出版日期 | 2021-08-01 |
| 卷号 | 17期号:8页码:1635-1646 |
| 关键词 | Gadolinium Coordination Polymer Dual-Mode Imaging Fluorescence Magnetic Resonance |
| ISSN号 | 1550-7033 |
| DOI | 10.1166/jbn.2021.3136 |
| 通讯作者 | Xu, Weibing(xuwb@gsau.edu.cn) ; Nian, Fang(nianf@gsau.edu.cn) |
| 英文摘要 | Due to the combination of the high resolution of fluorescence imaging and the no limitation in penetration depth of magnetic resonance imaging, dual-mode imaging of magnetic resonance and fluorescence (MR/FI) have attracted extensive research in recent years. Herein, a novel MR/FI bimodal imaging probe is facile fabricated by attaching the rhodamine fluorophore covalently to the surface of the Gd-phenolic coordination polymer nanoparticles. The contents of Gd3+ and RB of the as prepared probe are calculated to be 8.2% and 12.5%. The quantum yield of the probe is about 8.84% as well as red fluorescent emissive. The longitudinal r1 value is 6.94 mM-1 s-1 and the ratio r2/r1 is very low and about 1.22. Subsequently, the and MR imaging and fluorescence both in vitro and in vivo are performed. The metabolic pathways in vivo are inferred by studying the bio-distribution of the probe in major organs. The as-prepared probe exhibits excellent P: 49249253 194 On: Wed 22 Sep 202 06:11:59 imaging performance and biocompatibility, whicis conduive to its further application. |
| WOS关键词 | FACILE HYDROTHERMAL SYNTHESIS ; CARBON QUANTUM DOTS ; ELECTRODE MATERIALS ; CONTRAST AGENT ; PROBE ; CHEMOSENSOR ; COMPOSITES ; RHODAMINE ; FE3+ |
| 资助项目 | Natural Science Foundation of Gansu Province[20JR10RA511] ; Natural Science Foundation of Gansu Province[2019B-084] ; Scientific Research start-up funds for openly-recruited doctors of Gansu Agricultural University[2017RCZX-42] |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000701689400001 |
| 出版者 | AMER SCIENTIFIC PUBLISHERS |
| 资助机构 | Natural Science Foundation of Gansu Province ; Scientific Research start-up funds for openly-recruited doctors of Gansu Agricultural University |
| 源URL | [http://119.78.100.186/handle/113462/136291]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Xu, Weibing; Nian, Fang |
| 作者单位 | 1.Gansu Agr Univ, Coll Life Sci, Lanzhou 730000, Peoples R China 2.Gansu Agr Univ, Coll Sci, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Weibing,Zhang, Jia,Zhao, Minzhi,et al. Red Fluorescent Emissive Gd-Phenolic Nanoparticles for In Vivo Fluorescence and Magnetic Resonance Bimodal Imaging[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2021,17(8):1635-1646. |
| APA | Xu, Weibing,Zhang, Jia,Zhao, Minzhi,Yang, Zhijie,Wu, Qingfeng,&Nian, Fang.(2021).Red Fluorescent Emissive Gd-Phenolic Nanoparticles for In Vivo Fluorescence and Magnetic Resonance Bimodal Imaging.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,17(8),1635-1646. |
| MLA | Xu, Weibing,et al."Red Fluorescent Emissive Gd-Phenolic Nanoparticles for In Vivo Fluorescence and Magnetic Resonance Bimodal Imaging".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 17.8(2021):1635-1646. |
入库方式： OAI收割
来源：近代物理研究所
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