中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Individual and successive detection of H2S and HClO in living cells and zebrafish by a dual-channel fluorescent probe with longer emission wavelength

文献类型:期刊论文

作者Cheng, Wei3; Xue, Xuqi3; Gan, Lu4; Jin, Peng3; Zhang, Baoxin3; Guo, Menghuan4; Si, Jing4; Du, Hongying1; Chen, Hongli3; Fang, Jianguo3
刊名ANALYTICA CHIMICA ACTA
出版日期2021-04-29
卷号1156页码:9
关键词Dual-channel fluorescent probe HClO and H2S Turn-on Individual and successive detection Bioimaging
ISSN号0003-2670
DOI10.1016/j.aca.2021.338362
通讯作者Du, Hongying(hydu@mail.hzau.edu.cn) ; Chen, Hongli(hlchen@lzu.edu.cn)
英文摘要Reactive oxygen species (ROS) and reactive sulfur species (RSS) participate in many physiological activities and help maintaining the redox homeostasis in biological system. The complicated intrinsic connection between specific ROS/RSS needs to be further explored. Herein, a novel fluorescent probe (MB-NAP-N-3) with longer emission wavelength has been rationally designed and synthesized based on the conjugation of the methylene blue moiety and the naphthalimide moiety for the detection of hypochlorous acid (HClO) and hydrogen sulfide (H2S). The dual-signal probe exhibits rapid turn-on fluorescence responses for individual and successive detection of H2S and HClO in green and red channels, respectively. Owning to its advantages such as fast response, good selectivity and high sensitivity, the probe was successfully applied to detect endogenous and exogenous HClO/H2S in living cells. Furthermore, the outstanding luminescence performance makes it suitable for the visualization of the in vivo interaction between the two analytes in zebrafish. (C) 2021 Elsevier B.V. All rights reserved.
资助项目National Natural Science Foundation of China[21874060] ; Ministry of Science and Technology, National Key RD Project[2018YFE0205100]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000632679500001
出版者ELSEVIER
资助机构National Natural Science Foundation of China ; Ministry of Science and Technology, National Key RD Project
源URL[http://119.78.100.186/handle/113462/137727]  
专题中国科学院近代物理研究所
通讯作者Du, Hongying; Chen, Hongli
作者单位1.Huazhong Agr Univ, Coll Food Sci & Technol, Key Lab Environm Correlat Dietol, Minist Educ, Wuhan 430071, Peoples R China
2.Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China
3.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
4.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714
Cheng, Wei,Xue, Xuqi,Gan, Lu,et al. Individual and successive detection of H2S and HClO in living cells and zebrafish by a dual-channel fluorescent probe with longer emission wavelength[J]. ANALYTICA CHIMICA ACTA,2021,1156:9.
APA Cheng, Wei.,Xue, Xuqi.,Gan, Lu.,Jin, Peng.,Zhang, Baoxin.,...&Fang, Jianguo.(2021).Individual and successive detection of H2S and HClO in living cells and zebrafish by a dual-channel fluorescent probe with longer emission wavelength.ANALYTICA CHIMICA ACTA,1156,9.
MLA Cheng, Wei,et al."Individual and successive detection of H2S and HClO in living cells and zebrafish by a dual-channel fluorescent probe with longer emission wavelength".ANALYTICA CHIMICA ACTA 1156(2021):9.

入库方式: OAI收割

来源:近代物理研究所

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