DLEU2 participates in lymphovascular invasion and inhibits cervical cancer cell proliferation, and invasion
文献类型：期刊论文
| 作者 | Zhang, Hanqun1; Wang, Xiaohu1,3; Zhang, Qiuning1,2; Ma, Yan1; Wang, Zi4 |
| 刊名 | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY
 |
| 出版日期 | 2020 |
| 卷号 | 13期号:8页码:2018-2026 |
| 关键词 | Cervical cancer long non-coding RNA deleted in lymphocytic leukemia 2 |
| ISSN号 | 1936-2625 |
| 通讯作者 | Wang, Xiaohu(xhwanggansu@163.com) ; Wang, Zi(wz522321@163.com) |
| 英文摘要 | Aims: To investigate the roles of deleted in lymphocytic leukemia-2 (DLEU2) in the pathology of cervical cancer. Methods: Differentially expressed long non-coding RNAs between cervical cancerous and para-cancerous tissues were examined in 26 clinical specimens by microarray analysis and quantitative real-time PCR. DLEU2 ex-pression was correlated with clinical features in 108 patients with cervical cancer. The effects of DLEU2 on growth, proliferation, migration, and invasion were examined in cervical cancer cells. Results: DLEU2 was correlated with lymphovascular invasion in patients with cervical cancer. DLEU2 overexpression inhibited cell proliferation, migra-tion, and proliferation, and colony formation in cervical cancer cells. Conclusion: DLEU2 is involved in the pathology of cervical cancer, and it may be a target for clinical therapy. |
| WOS关键词 | LONG NONCODING RNAS ; CARCINOMA ; EXPRESSION ; 13Q14 ; RISK ; GENE |
| 资助项目 | Guizhou Innovation and Entrepreneurship Foundation for High-level Overseas Talent[[2019] 03] ; National Natural Science Foundation of China[81860535] |
| WOS研究方向 | Oncology ; Pathology |
| 语种 | 英语 |
| WOS记录号 | WOS:000573059000008 |
| 出版者 | E-CENTURY PUBLISHING CORP |
| 资助机构 | Guizhou Innovation and Entrepreneurship Foundation for High-level Overseas Talent ; National Natural Science Foundation of China |
| 源URL | [http://119.78.100.186/handle/113462/139633]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Wang, Xiaohu; Wang, Zi |
| 作者单位 | 1.Lanzhou Univ, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Gansu, Peoples R China 3.Gansu Prov Canc Hosp, Lanzhou 730000, Gansu, Peoples R China 4.Guizhou Prov Peoples Hosp, Dept Oncol, Guiyang 550002, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hanqun,Wang, Xiaohu,Zhang, Qiuning,et al. DLEU2 participates in lymphovascular invasion and inhibits cervical cancer cell proliferation, and invasion[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY,2020,13(8):2018-2026. |
| APA | Zhang, Hanqun,Wang, Xiaohu,Zhang, Qiuning,Ma, Yan,&Wang, Zi.(2020).DLEU2 participates in lymphovascular invasion and inhibits cervical cancer cell proliferation, and invasion.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY,13(8),2018-2026. |
| MLA | Zhang, Hanqun,et al."DLEU2 participates in lymphovascular invasion and inhibits cervical cancer cell proliferation, and invasion".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 13.8(2020):2018-2026. |
入库方式： OAI收割
来源：近代物理研究所
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