Role of miR-302/367 cluster in human physiology and pathophysiology
文献类型：期刊论文
| 作者 | Guo, Menghuan1; Gan, Lu4,5,6 ; Si, Jing4,5,6; Zhang, Jinhua4,5,6; Liu, Zhiyuan3; Zhao, Jin2; Gou, Zhong2; Zhang, Hong1,4,5,6
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| 刊名 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
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| 出版日期 | 2020-08-01 |
| 卷号 | 52期号:8页码:791-800 |
| 关键词 | miR-302/367 cluster pluripotent stem cells cancer central nervous system cardiovascular system |
| ISSN号 | 1672-9145 |
| DOI | 10.1093/abbs/gmaa065 |
| 通讯作者 | Zhang, Hong(zhangh@impcas.ac.cn) |
| 英文摘要 | MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate target mRNAs at the post-transcriptional level. Increasing evidence shows the involvement of miRNAs in diverse biological processes. miR-302/367 cluster is highly conserved among vertebrates and made up of five members, including miR-367, miR-302a, miR-302b, miR-302c and miR-302d. miR-302/367 cluster plays an important role in cell proliferation, differentiation and reprogramming, affecting the development of tumor, cardiovascular system, nervous system and immune system. In this review, we will summarize the role of miR-302/367 cluster in embryonic stem cells and induced pluripotent stem cells and try to point out its relationship with tumors, cardiovascular system, nervous system and immune system. |
| WOS关键词 | MIR-367 PROMOTES PROLIFERATION ; EMBRYONIC STEM-CELLS ; HEPATOCELLULAR-CARCINOMA ; CARDIOMYOCYTE PROLIFERATION ; UNFAVORABLE PROGNOSIS ; CYCLIN D1 ; MICRORNA ; EXPRESSION ; SUPPRESSES ; INVASION |
| 资助项目 | Ministry of Science and Technology National Key RD Project[2018YFE0205100] ; National Natural Science Foundation of China[31560254] ; National Natural Science Foundation of China[81960337] ; National Natural Science Foundation of China[81560508] ; National Natural Science Foundation of China[11775289] ; Fundamental Research Funds for the Central Universities[31920160048] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| WOS记录号 | WOS:000574289000001 |
| 出版者 | OXFORD UNIV PRESS |
| 资助机构 | Ministry of Science and Technology National Key RD Project ; National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities |
| 源URL | [http://119.78.100.186/handle/113462/139687]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Zhang, Hong |
| 作者单位 | 1.Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China 2.Northwest Minzu Univ, Med Coll, Lanzhou 730030, Peoples R China 3.Northwest Minzu Univ, Sch Chem Engn, Lanzhou 730030, Peoples R China 4.Univ Chinese Acad Sci, Sch Nucl Sci & Technol, Beijing 100049, Peoples R China 5.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Peoples R China 6.Chinese Acad Sci, Biomed Res Ctr, Inst Modern Phys, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, Menghuan,Gan, Lu,Si, Jing,et al. Role of miR-302/367 cluster in human physiology and pathophysiology[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2020,52(8):791-800. |
| APA | Guo, Menghuan.,Gan, Lu.,Si, Jing.,Zhang, Jinhua.,Liu, Zhiyuan.,...&Zhang, Hong.(2020).Role of miR-302/367 cluster in human physiology and pathophysiology.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,52(8),791-800. |
| MLA | Guo, Menghuan,et al."Role of miR-302/367 cluster in human physiology and pathophysiology".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 52.8(2020):791-800. |
入库方式： OAI收割
来源：近代物理研究所
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