Biomarkers of Brain Damage Induced by Radiotherapy
文献类型：期刊论文
| 作者 | Sultana, Nahida1; Sun, Chao2 ; Katsube, Takanori3; Wang, Bing3
|
| 刊名 | DOSE-RESPONSE
 |
| 出版日期 | 2020-07-01 |
| 卷号 | 18期号:3页码:10 |
| 关键词 | biomarker cranial radiotherapy radiation-induced brain damage cognitive impairment |
| ISSN号 | 1559-3258 |
| DOI | 10.1177/1559325820938279 |
| 通讯作者 | Sultana, Nahida(kochi.haque2012@gmail.com) ; Wang, Bing(wang.bing@qst.go.jp) |
| 英文摘要 | Radiotherapy remains currently a critical component for both primary and metastatic brain tumors either alone or in combination with surgery, chemotherapy, and molecularly targeted agents, while it could cause simultaneously normal brain tissue injury leading to serious health consequences, that is, development of cognitive impairments following cranial radiotherapy is considered as a critical clinical disadvantage especially for the whole brain radiotherapy. Biomarkers can help to detect the accurate physiology or conditions of patients with brain tumor and develop effective treatment procedures for these patients. In the near future, biomarkers will become one of the prime driving forces of cancer treatment. In this minireview, we analyze the documented work on the acute brain damage and late consequences induced by radiotherapy, identify the biomarkers, in particular, the predictive biomarkers for the damage, and summarize the biological significance of the biomarkers. It is expected that translation of these research advance to radiotherapy would assist stratifying patients for optimized treatment and improving therapeutic efficacy and the quality of life. |
| WOS关键词 | CENTRAL-NERVOUS-SYSTEM ; ENDOTHELIAL GROWTH-FACTOR ; APPEARING WHITE-MATTER ; MAGNETIC-RESONANCE-SPECTROSCOPY ; RADIATION-INDUCED CHANGES ; DIFFUSION TENSOR ; NORMAL TISSUE ; CRANIAL IRRADIATION ; STEREOTACTIC RADIOSURGERY ; PROGNOSTIC-SIGNIFICANCE |
| 资助项目 | Ministry of Education, Culture, Sport, Sciences and Technology (MEXT)[15H05935] ; MEXT, Japan ; Nuclear Safety Research Association, Japan |
| WOS研究方向 | Pharmacology & Pharmacy ; Radiology, Nuclear Medicine & Medical Imaging ; Toxicology |
| 语种 | 英语 |
| WOS记录号 | WOS:000551666400001 |
| 出版者 | SAGE PUBLICATIONS INC |
| 资助机构 | Ministry of Education, Culture, Sport, Sciences and Technology (MEXT) ; MEXT, Japan ; Nuclear Safety Research Association, Japan |
| 源URL | [http://119.78.100.186/handle/113462/140228]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Sultana, Nahida; Wang, Bing |
| 作者单位 | 1.Bangladesh Atom Energy Commiss, Atom Energy Res Estab, Inst Food & Radiat Biol, Dhaka 1207, Bangladesh 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou, Peoples R China 3.Natl Inst Quantum & Radiol Sci & Technol, Natl Inst Radiol Sci, Chiba 2638555, Japan |
| 推荐引用方式 GB/T 7714 | Sultana, Nahida,Sun, Chao,Katsube, Takanori,et al. Biomarkers of Brain Damage Induced by Radiotherapy[J]. DOSE-RESPONSE,2020,18(3):10. |
| APA | Sultana, Nahida,Sun, Chao,Katsube, Takanori,&Wang, Bing.(2020).Biomarkers of Brain Damage Induced by Radiotherapy.DOSE-RESPONSE,18(3),10. |
| MLA | Sultana, Nahida,et al."Biomarkers of Brain Damage Induced by Radiotherapy".DOSE-RESPONSE 18.3(2020):10. |
入库方式： OAI收割
来源：近代物理研究所
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