中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 近代物理研究所
  3. 中国科学院近代物理研究所
The supplement of vitamin C facilitates L-lactic acid biosynthesis in Lactobacillus thermophilus A69 from sweet sorghum juice coupled with soybean hydrolysate as feedstocks

文献类型：期刊论文

作者Tian, Xuejiao2,3; Hu, Wei2,3; Chen, Jihong2,3; Zhang, Wei1; Li, Wenjian2,3
刊名INDUSTRIAL CROPS AND PRODUCTS
出版日期2020-04-01
卷号146页码:7
ISSN号0926-6690
关键词Vitamin C L-lactic acid Sweet sorghum juice Antioxidant capacity Fermentation efficiency
DOI10.1016/j.indcrop.2020.112159
通讯作者Hu, Wei(hudongli007@impcas.ac.cn)
英文摘要Regulating oxidative damage is an effective way to enhance cell growth and metabolite accumulation in microbial strains. However, this strategy on lactic acid production has not been systematically reported yet. In present study, the effect of antioxidant vitamin C on cell growth and L-lactic acid production was investigated in Lactobacillus thermophilus A69, and an addition of 75 mM vitamin C resulted in significant improvement in cell growth and L-lactic acid accumulation. The total antioxidant capacity (T-AOC) and key enzyme activities involving in glycolytic pathway (such as hexokinase, phosphofructokinase, pyruvate kinase, and lactate dehydrogenase) were also significantly enhanced by vitamin C addition. Finally, with the addition of optimal concentrations of vitamin C into sweet sorghum juice coupled with cheaper soybean hydrolysate as feedstocks, a final L-lactic acid titer of 118.8 g/L with the productivity of 3.71 g/L/h was achieved by A69 strain. This study provided an efficient and economical approach for enhancement of L-lactic acid fermentation efficiency using sweet sorghum juice as a feedstock.
WOS关键词REPEATED-BATCH FERMENTATION ; BACILLUS-COAGULANS ; NITROGEN-SOURCE ; DOCOSAHEXAENOIC ACID ; ENHANCED PRODUCTION ; RHAMNOSUS ; OPTIMIZATION ; PRODUCTIVITY ; ANTIOXIDANT ; IMPROVEMENT
资助项目National Natural Science Foundation of China[U1932136] ; Western Talents Program of the Chinese Academy of Sciences[Y706030XB0] ; Open Funds of Key Laboratory of Extreme Environmental Microbial Resources and Engineering, Gansu Province[EEMRE201801]
WOS研究方向Agriculture
语种英语
出版者ELSEVIER
WOS记录号WOS:000519335100028
资助机构National Natural Science Foundation of China ; Western Talents Program of the Chinese Academy of Sciences ; Open Funds of Key Laboratory of Extreme Environmental Microbial Resources and Engineering, Gansu Province
源URL[http://119.78.100.186/handle/113462/140596]  
专题中国科学院近代物理研究所
通讯作者Hu, Wei
作者单位1.Chinese Acad Sci, Northwest Inst Ecoenvironm & Resources, Key Lab Extreme Environm Microbial Resources & En, Lanzhou 730000, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, Lanzhou, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Tian, Xuejiao,Hu, Wei,Chen, Jihong,et al. The supplement of vitamin C facilitates L-lactic acid biosynthesis in Lactobacillus thermophilus A69 from sweet sorghum juice coupled with soybean hydrolysate as feedstocks[J]. INDUSTRIAL CROPS AND PRODUCTS,2020,146:7.
APA Tian, Xuejiao,Hu, Wei,Chen, Jihong,Zhang, Wei,&Li, Wenjian.(2020).The supplement of vitamin C facilitates L-lactic acid biosynthesis in Lactobacillus thermophilus A69 from sweet sorghum juice coupled with soybean hydrolysate as feedstocks.INDUSTRIAL CROPS AND PRODUCTS,146,7.
MLA Tian, Xuejiao,et al."The supplement of vitamin C facilitates L-lactic acid biosynthesis in Lactobacillus thermophilus A69 from sweet sorghum juice coupled with soybean hydrolysate as feedstocks".INDUSTRIAL CROPS AND PRODUCTS 146(2020):7.

入库方式： OAI收割

来源：近代物理研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。