Bioaccumulation investigation of bisphenol A in HepG2 cells and zebrafishes enabled by cobalt magnetic polystyrene microsphere derived carbon based magnetic solid-phase extraction
文献类型：期刊论文
| 作者 | Niu, Panhong1,2,3; Lu, Xiaofeng1,2; Liu, Bingtao3,4; Li, Yijing1,2; Liang, Xiaojing1,2; Wang, Shuai1,2; Guo, Yong1,2 |
| 刊名 | ANALYST
 |
| 出版日期 | 2020-02-21 |
| 卷号 | 145期号:4页码:1433-1444 |
| ISSN号 | 0003-2654 |
| DOI | 10.1039/c9an02324k |
| 通讯作者 | Wang, Shuai(shuaiw@licp.cas.cn) ; Guo, Yong(guoyong@licp.cas.cn) |
| 英文摘要 | A magnetic solid-phase extraction (MSPE) technique coupled with high performance liquid chromatography (HPLC) was developed and used for bioaccumulation investigation of bisphenol A (BPA) in HepG2 cells and zebrafishes. Cobalt magnetic polystyrene microsphere derived carbon (C-Co@PST) as an adsorbent was prepared by in situ polymerization reaction and further annealing treatment. Scanning electron microscopy, energy-dispersive X-ray spectroscopy, Fourier transform infrared spectrometry, X-ray photoelectron spectroscopy and X-ray diffraction were employed to confirm successful synthesis of C-Co@PST. A series of extraction parameters including the amount of the sorbent, the type of elute, extraction time and elution time were investigated to achieve high extraction efficiency. C-Co@PST based MSPE combined with HPLC was successfully established for bioaccumulation research of BPA in living creatures. It was found that the bioconcentration values of BPA in HepG2 cells underwent an increase, then a decrease, and finally reached an equilibrium level of 11.60 mu g kg(-1) at 8 h. The concentration of BPA in zebrafishes increased ranging from 6.05 mu g kg(-1) to 31.84 mu g kg(-1) over a culture time from 1 h to 12 h. Furthermore, linear and exponential models were employed to analyse the bioconcentration variation of BPA in organisms over the exposure time. Mathematical models have been developed to predict the transfer characteristics of BPA. |
| WOS关键词 | ENDOCRINE DISRUPTING CHEMICALS ; GRAPHENE OXIDE ; WATER ; ADSORPTION ; POLYMERIZATION ; NANOPARTICLES ; SURFACTANTS ; COMPOSITE ; SAMPLES ; FISHES |
| 资助项目 | National Natural Science Foundation of China[21575149] ; National Natural Science Foundation of China[21575148] ; State Key Scientific Special Project[2016ZX05011-003] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000515832700035 |
| 资助机构 | National Natural Science Foundation of China ; State Key Scientific Special Project |
| 源URL | [http://119.78.100.186/handle/113462/141021]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Wang, Shuai; Guo, Yong |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, CAS Key Lab Chem Northwestern Plant Resource, Lanzhou 730000, Gansu, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Gansu, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Modern Phys, Dept Med Phys, Lanzhou 730000, Gansu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Niu, Panhong,Lu, Xiaofeng,Liu, Bingtao,et al. Bioaccumulation investigation of bisphenol A in HepG2 cells and zebrafishes enabled by cobalt magnetic polystyrene microsphere derived carbon based magnetic solid-phase extraction[J]. ANALYST,2020,145(4):1433-1444. |
| APA | Niu, Panhong.,Lu, Xiaofeng.,Liu, Bingtao.,Li, Yijing.,Liang, Xiaojing.,...&Guo, Yong.(2020).Bioaccumulation investigation of bisphenol A in HepG2 cells and zebrafishes enabled by cobalt magnetic polystyrene microsphere derived carbon based magnetic solid-phase extraction.ANALYST,145(4),1433-1444. |
| MLA | Niu, Panhong,et al."Bioaccumulation investigation of bisphenol A in HepG2 cells and zebrafishes enabled by cobalt magnetic polystyrene microsphere derived carbon based magnetic solid-phase extraction".ANALYST 145.4(2020):1433-1444. |
入库方式： OAI收割
来源：近代物理研究所
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