Advances in Mitochondrial Ultrastructure and Its Regulatory Mechanism
文献类型：期刊论文
| 作者 | Huang Guo-Min1,2,3,4; Wang Yu-Pei5; Sun Chao1,2,3,4 ; Zhang Xue-Tian1,2,3,4; Zhang Hong1,2,3,4
|
| 刊名 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
 |
| 出版日期 | 2019-12-01 |
| 卷号 | 46期号:12页码:1141-1149 |
| 关键词 | mitochondria ultrastructure Crista junction MICOS F1F0-ATP synthase |
| ISSN号 | 1000-3282 |
| DOI | 10.16476/j.pibb.2019.0142 |
| 通讯作者 | Zhang Hong(zhangh@impcas.ac.cn) |
| 英文摘要 | Mitochondrial ultrastructure is a fine structure observed by electron microscope, which can be changed according to different energy requirements and physiological environment, and plays a key role in regulating mitochondrial function. The structure of mitochondrial cristae is an important mitochondrial ultrastructure, which affects many mitochondrial diseases. Therefore, studying the function and understanding the regulation mechanism of mitochondrial ultrastructure have important guiding significance for studying mitochondrial diseases and looking for therapeutic targets. This paper introduces the main regulating mechanism of mitochondrial cristae in detail, and focuses on the research progress in the composition of mitochondrial ultrastructure, the effect of mitochondrial ultrastructure on mitochondrial function, and the relationship between mitochondrial ultrastructure and mitochondrial disease, in order to provide theoretical reference for developing more effective mitochondrial disease treatment. |
| WOS关键词 | DOMINANT OPTIC ATROPHY ; CONTACT SITE ; COMPLEX I ; MEMBRANE ARCHITECTURE ; PARKINSONS-DISEASE ; ORGANIZING SYSTEM ; CALCIUM UNIPORTER ; CA2+ UNIPORTER ; BARTH SYNDROME ; ATP SYNTHASE |
| 资助项目 | Ministry of Science and Technology National Key RD Project[SQ2018YFE020524] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| WOS记录号 | WOS:000504952900001 |
| 出版者 | CHINESE ACAD SCIENCES, INST BIOPHYSICS |
| 资助机构 | Ministry of Science and Technology National Key RD Project |
| 源URL | [http://119.78.100.186/handle/113462/141348]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Zhang Hong |
| 作者单位 | 1.Univ Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Gansu, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Gansu, Peoples R China 4.Key Lab Heavy Ion Radiat Med Gansu Prov, Lanzhou 730000, Gansu, Peoples R China 5.Gansu Prov Maternal & Child Hlth Care Ctr, Lanzhou 730000, Gansu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang Guo-Min,Wang Yu-Pei,Sun Chao,et al. Advances in Mitochondrial Ultrastructure and Its Regulatory Mechanism[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2019,46(12):1141-1149. |
| APA | Huang Guo-Min,Wang Yu-Pei,Sun Chao,Zhang Xue-Tian,&Zhang Hong.(2019).Advances in Mitochondrial Ultrastructure and Its Regulatory Mechanism.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,46(12),1141-1149. |
| MLA | Huang Guo-Min,et al."Advances in Mitochondrial Ultrastructure and Its Regulatory Mechanism".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 46.12(2019):1141-1149. |
入库方式： OAI收割
来源：近代物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。