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A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics

文献类型：期刊论文

作者Long, Huali1; Yao, Shuai1; Tian, Wenshuai2; Hou, Jinjun1; Lei, Min1; Zhang, Zijia1; Guo, Dean1; Wu, Wanying1
刊名JOURNAL OF SEPARATION SCIENCE
出版日期2021-12-19
页码16
关键词chemometrics Fraxini Cortex high-performance thin-layer chromatography multi-mode fingerprint ultra-high-performance liquid chromatography
ISSN号1615-9306
DOI10.1002/jssc.202100784
通讯作者Guo, Dean(daguo@simm.ac.cn) ; Wu, Wanying(wanyingwu@simm.ac.cn)
英文摘要Fraxini Cortex has a long history of being used as a medicinal plant in traditional Chinese medicine. However, it is challenging to differentiate and make quality evaluations for Fraxini Cortex from different origins due to their similarities in morphological features, as well as general chemical composition using traditional chemical analytical methods. In this study, a simple and effective method was developed to identify Fraxini Cortex from different origins by multi-mode fingerprint combined with chemometrics. Digital images of the high-performance thin-layer chromatography profiles were converted to grayscale intensity, and the common patterns of high-performance thin-layer chromatography fingerprints were generated with ChemPattern software. Authentication and quality assessment were analyzed by similarity analysis, hierarchical cluster analysis, principal component analysis, and multivariate analysis of variance. The ultra-high-performance liquid chromatography fingerprints were analyzed by similarity analysis, principal component analysis, and orthogonal partial least square-discriminant analysis. When combined with chemometrics, high-performance thin-layer chromatography and ultra-high-performance liquid chromatography fingerprint provided a simple and effective method to evaluate the comprehensive quality of Fraxini Cortex, and to distinguish its two original medicinal materials (Fraxinus chinensis Roxb. and Fraxinus rhynchophylla Hance.) recorded in the Chinese Pharmacopeia and its three adulterants (Fraxinus mandschurica Rupr., Fraxinus pennsylvanica Marsh., and Juglans mandshurica Maxim.). A similar workflow may be applied to establish a differentiation method for other medicinal and economic plants.
资助项目National Natural Science Foundation of China[81803713] ; National Key R&D Program of China[2018YFC1707900] ; National Key R&D Program of China[2018YFC1707903] ; National Key R&D Program of China[2018YFC1707905] ; National Key R&D Program of China[2018YFC1707001]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000731406700001
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/299250]  
专题中国科学院上海药物研究所
通讯作者Guo, Dean; Wu, Wanying
作者单位1.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, 501 Haike Rd, Shanghai 201203, Peoples R China
2.Shanghai Stand Technol Co Ltd, Shanghai 201314, Peoples R China
推荐引用方式
GB/T 7714		 Long, Huali,Yao, Shuai,Tian, Wenshuai,et al. A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics[J]. JOURNAL OF SEPARATION SCIENCE,2021:16.
APA Long, Huali.,Yao, Shuai.,Tian, Wenshuai.,Hou, Jinjun.,Lei, Min.,...&Wu, Wanying.(2021).A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics.JOURNAL OF SEPARATION SCIENCE,16.
MLA Long, Huali,et al."A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics".JOURNAL OF SEPARATION SCIENCE (2021):16.

入库方式： OAI收割

来源：上海药物研究所

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