Progress and Perspective on Carbon-Based Nanozymes for Peroxidase-like Applications
文献类型：期刊论文
| 作者 | Wang, Xingyu1,2; Wang, Hui1,2,3; Zhou, Shuiqin4,5 |
| 刊名 | JOURNAL OF PHYSICAL CHEMISTRY LETTERS
 |
| 出版日期 | 2021-12-09 |
| 卷号 | 12 |
| ISSN号 | 1948-7185 |
| DOI | 10.1021/acs.jpclett.1c03219 |
| 通讯作者 | Wang, Hui(hw39@hmfl.ac.cn) ; Zhou, Shuiqin(Shuiqin.Zhou@csi.cuny.edu) |
| 英文摘要 | Tumor microenvironment-responsive chemodynamic therapy (CDT), an approach based on Fenton/Fenton-like reaction to convert hydrogen peroxide (H2O2) into the highly cytotoxic hydroxyl radical (center dot OH) in situ to kill cancer cells, represents an important direction for cancer therapy. Different types of nanozymes (nanomaterial-based catalysts that can mimic the activities of natural enzymes) have been developed to mimic peroxidase. This Perspective highlights the latest research progress regarding low-cost and biocompatible carbon-based nanozymes for peroxidase mimics. The effects of structure and surface properties of carbon-based nanozymes on their electronic transfer and peroxidase-like activity are analyzed, including nanospheres, nanotubes, nanosheets, and graphene quantum dots (GQDs) with or without surface functionalization and heteroatom doping. We expand our newly developed carbon nitride (g-C3N4) QD systems to nanozyme application, which are highly efficient in converting the intracellular H2O2 to center dot OH species to kill 4T1 cancer cells and demonstrate a great potential for CDT. |
| WOS关键词 | COLORIMETRIC DETECTION ; CANCER STATISTICS ; GOLD ; GRAPHENE ; ACTIVATION ; NANOSHEETS ; MECHANISM ; SITES |
| 资助项目 | National Natural Science Foundation of China[U2032162] ; Collaborative Innovation Program of Hefei Science Center of CAS[2019HSC-CIP012] ; PSC-CUNY Research Award[63210-00 51] ; High Magnetic Field Laboratory of Anhui Province |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000751669500019 |
| 出版者 | AMER CHEMICAL SOC |
| 资助机构 | National Natural Science Foundation of China ; Collaborative Innovation Program of Hefei Science Center of CAS ; PSC-CUNY Research Award ; High Magnetic Field Laboratory of Anhui Province |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/127497]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Wang, Hui; Zhou, Shuiqin |
| 作者单位 | 1.Chinese Acad Sci, Hefei Inst Phys Sci, High Magnet Field Lab, Hefei 230031, Anhui, Peoples R China 2.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China 3.Chinese Acad Sci, Hefei Inst Phys Sci, Anhui Key Lab Condensed Matter Phys Extreme Condi, Hefei 230031, Anhui, Peoples R China 4.CUNY Coll Staten Isl, Dept Chem, Staten Isl, NY 10314 USA 5.CUNY, Grad Ctr, PhD Program Chem, Staten Isl, NY 10314 USA |
| 推荐引用方式 GB/T 7714 | Wang, Xingyu,Wang, Hui,Zhou, Shuiqin. Progress and Perspective on Carbon-Based Nanozymes for Peroxidase-like Applications[J]. JOURNAL OF PHYSICAL CHEMISTRY LETTERS,2021,12. |
| APA | Wang, Xingyu,Wang, Hui,&Zhou, Shuiqin.(2021).Progress and Perspective on Carbon-Based Nanozymes for Peroxidase-like Applications.JOURNAL OF PHYSICAL CHEMISTRY LETTERS,12. |
| MLA | Wang, Xingyu,et al."Progress and Perspective on Carbon-Based Nanozymes for Peroxidase-like Applications".JOURNAL OF PHYSICAL CHEMISTRY LETTERS 12(2021). |
入库方式： OAI收割
来源：合肥物质科学研究院
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