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Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives

文献类型：期刊论文

作者Wu, Qiong; Han, Ting-Shen; Chen, Xi; Chen, Jia-Fu; Zou, Yu-Pan; Li, Zi-Wen; Xu, Yong-Chao; Guo, Ya-Long
刊名GENOME BIOLOGY
出版日期2017
卷号18
关键词Adaptation Arabidopsis thaliana Balancing selection Capsella rubella Trans-species polymorphism
ISSN号1474-760X
DOI10.1093/botlinnean/box036
文献子类Article
英文摘要Background: In contrast to positive selection, which reduces genetic variation by fixing beneficial alleles, balancing selection maintains genetic variation within a population or species and plays crucial roles in adaptation in diverse organisms. However, which genes, genome-wide, are under balancing selection and the extent to which these genes are involved in adaptation are largely unknown. Results: We performed a genome-wide scan for genes under balancing selection across two plant species, Arabidopsis thaliana and its relative Capsella rubella, which diverged about 8 million generations ago. Among hundreds of genes with shared coding-region polymorphisms, we find evidence for long-term balancing selection in five genes: AT1G35220, AT2G16570, AT4G29360, AT5G38460, and AT5G44000. These genes are involved in the response to biotic and abiotic stress and other fundamental biochemical processes. More intriguingly, for these genes, we detected significant ecological diversification between the two haplotype groups, suggesting that balancing selection has been very important for adaptation. Conclusions: Our results indicate that beyond the well-known S-locus genes and resistance genes, many loci are under balancing selection. These genes are mostly correlated with resistance to stress or other fundamental functions and likely play a more important role in adaptation to diverse habitats than previously thought.
学科主题Plant Sciences
出版地LONDON
WOS关键词CAPSELLA-RUBELLA ; TRANSSPECIES POLYMORPHISM ; RECENT SPECIATION ; S-LOCUS ; GENOME ; THALIANA ; EVOLUTION ; RESISTANCE ; MAINTAINS ; HISTORY
语种英语
WOS记录号WOS:000406943300003
出版者BMC
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [91231104, 31222006, 31470331, 61103066] ; 100 Talents Program of the Chinese Academy of SciencesChinese Academy of Sciences
源URL[http://ir.ibcas.ac.cn/handle/2S10CLM1/22285]  
专题植物研究所_系统与进化植物学研究中心_系统与进化植物学研究中心_学位论文
作者单位1.Chen, Xi
2.[Han, Ting-Shen
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Li, Zi-Wen
5.Zou, Yu-Pan
6.Chen, Jia-Fu
7.Xu, Yong-Chao
8.[Wu, Qiong
9.Han, Ting-Shen
10.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China
推荐引用方式
GB/T 7714		 Wu, Qiong,Han, Ting-Shen,Chen, Xi,et al. Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives[J]. GENOME BIOLOGY,2017,18.
APA Wu, Qiong.,Han, Ting-Shen.,Chen, Xi.,Chen, Jia-Fu.,Zou, Yu-Pan.,...&Guo, Ya-Long.(2017).Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives.GENOME BIOLOGY,18.
MLA Wu, Qiong,et al."Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives".GENOME BIOLOGY 18(2017).

入库方式： OAI收割

来源：植物研究所

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