F-Type ATP Synthase Assembly Factors Atp11 and Atp12 in Arabidopsis
文献类型：期刊论文
| 作者 | Duan, Zhikun; Li, Kaiwen; Zhang, Lin2; Che, Liping2; Lu, Lizhen1; Rochaix, Jean-David; Lu, Congming3; Peng, Lianwei2 |
| 刊名 | FRONTIERS IN PLANT SCIENCE
 |
| 出版日期 | 2020 |
| 卷号 | 11 |
| 关键词 | ATP synthase assembly chloroplast mitochondria Atp11 Atp12 |
| ISSN号 | 1664-462X |
| DOI | 10.3389/fpls.2020.522753 |
| 文献子类 | Article |
| 英文摘要 | Atp11p and Atp12p are members of two chaperone families essential for assembly of the mitochondrial ATP synthase in Saccharomyces cerevisiae and Homo sapiens. However, the role of their homologs in higher plants is unclear with regard to the assembly of both chloroplast ATP synthase (cpATPase) and mitochondrial ATP synthase (mtATPase). Here, we show that loss of either Atp11 or Atp12 is lethal in Arabidopsis. While Atp12 is only localized in mitochondria, Atp11 is present both in chloroplasts and mitochondria. Yeast two-hybrid analyses showed that, as their homologs in yeast, Atp11 specifically interacts with the beta subunit of the mtATPase and cpATPase, and Atp12 interacts with the alpha subunit of the mtATPase, implying that Atp11 and Atp12 fulfill a conserved task during assembly of ATP synthase. However, the binding sites for Atp11 in the beta subunit of mtATPase and cpATPase are slightly different, suggesting that the mechanisms of action may have evolved in different ways. Although Atp11 interacts with cpATPase beta subunit as the two assembly factors BFA3 and BFA1, they bind to different sites of the beta subunit. These results indicate that Atp11 is involved in the assembly of both cpATPase and mtATPase but Atp12 is specifically required for the assembly of mtATPase in higher plants. |
| 学科主题 | Plant Sciences |
| 出版地 | LAUSANNE |
| WOS关键词 | BIOGENESIS ; F-1-ATPASE ; CHAPERONES ; SUBUNIT |
| WOS研究方向 | Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000583972200001 |
| 出版者 | FRONTIERS MEDIA SA |
| 资助机构 | China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2019M652522] ; Shanghai Engineering Research Center of Plant Germplasm Resources [17DZ2252700] |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/21536]  |
| 专题 | 中科院光生物学重点实验室 |
| 作者单位 | 1.Shanghai Normal Univ, Coll Life Sci, Shanghai Key Lab Plant Mol Sci, Shanghai, Peoples R China 2.Henan Univ, Sch Life Sci, State Key Lab Crop Stress Adaptat & Improvement, Kaifeng, Peoples R China 3.Univ Geneva, Dept Plant Biol, Geneva, Switzerland 4.Univ Geneva, Dept Mol Biol, Geneva, Switzerland 5.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Beijing, Peoples R China 6.Shandong Agr Univ, Coll Life Sci, State Key Lab Crop Biol, Tai An, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Duan, Zhikun,Li, Kaiwen,Zhang, Lin,et al. F-Type ATP Synthase Assembly Factors Atp11 and Atp12 in Arabidopsis[J]. FRONTIERS IN PLANT SCIENCE,2020,11. |
| APA | Duan, Zhikun.,Li, Kaiwen.,Zhang, Lin.,Che, Liping.,Lu, Lizhen.,...&Peng, Lianwei.(2020).F-Type ATP Synthase Assembly Factors Atp11 and Atp12 in Arabidopsis.FRONTIERS IN PLANT SCIENCE,11. |
| MLA | Duan, Zhikun,et al."F-Type ATP Synthase Assembly Factors Atp11 and Atp12 in Arabidopsis".FRONTIERS IN PLANT SCIENCE 11(2020). |
入库方式： OAI收割
来源：植物研究所
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