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Preparation and MRI performance of a composite contrast agent based on palygorskite pores and channels binding effect to prolong the residence time of water molecules on gadolinium ions

文献类型：期刊论文

作者Zhao, Minzhi1; Tang, Zhonghua2; Zhang, Jia1; Fu, Guorui1; Xu, Weibing1; Wu, Qingfeng3; Pu, Lumei1
刊名RSC ADVANCES
出版日期2022-03-01
卷号12期号:12页码:7328-7334
DOI10.1039/d1ra08967f
通讯作者Xu, Weibing(xuwb@gsau.edu.cn) ; Pu, Lumei()
英文摘要Herein, gadolinium tannate was simply and conveniently coated on the surface of palygorskite by in situ reaction of a coordination polymer formed between tannic acid and Gd3+. The palygorskite-tannate gadolinium-polyvinyl alcohol integrated composite (PAL@Gd@PVA) is successfully prepared after the introduction of polyvinyl alcohol onto the palygorskite-tannate gadolinium. The structure is characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis, X-ray diffraction spectroscopy, X-ray photoelectron spectroscopy, and transmission electron microscopy analysis. The results show that TA-Gd and PVA are successfully loaded on the surface of palygorskite, and the rod crystal structure of palygorskite in the composite remains intact. Palygorskite fibres constitute the framework of the composite and play a key role in supporting and crosslinking the composite. The prepared compounds showed negligible cytotoxicity and low haemolysis rate, showing good biocompatibility. In vitro MRI results showed that the longitudinal and transverse relaxation rates of the composite are 59.56 and 340.81 mm(-1) s(-1), respectively.
WOS关键词RESONANCE ; ATTAPULGITE
资助项目Natural Science Foundation of Gansu Province[20JR10RA511] ; Natural Science Foundation of Gansu Province[2019B-084]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000764251400001
出版者ROYAL SOC CHEMISTRY
资助机构Natural Science Foundation of Gansu Province
源URL[http://119.78.100.186/handle/113462/142014]  
专题中国科学院近代物理研究所
通讯作者Xu, Weibing; Pu, Lumei
作者单位1.Gansu Agr Univ, Coll Sci, Lanzhou 730000, Peoples R China
2.PetroChina, Lanzhou Petrochem Res Ctr, Lanzhou 730060, Peoples R China
3.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714		 Zhao, Minzhi,Tang, Zhonghua,Zhang, Jia,et al. Preparation and MRI performance of a composite contrast agent based on palygorskite pores and channels binding effect to prolong the residence time of water molecules on gadolinium ions[J]. RSC ADVANCES,2022,12(12):7328-7334.
APA Zhao, Minzhi.,Tang, Zhonghua.,Zhang, Jia.,Fu, Guorui.,Xu, Weibing.,...&Pu, Lumei.(2022).Preparation and MRI performance of a composite contrast agent based on palygorskite pores and channels binding effect to prolong the residence time of water molecules on gadolinium ions.RSC ADVANCES,12(12),7328-7334.
MLA Zhao, Minzhi,et al."Preparation and MRI performance of a composite contrast agent based on palygorskite pores and channels binding effect to prolong the residence time of water molecules on gadolinium ions".RSC ADVANCES 12.12(2022):7328-7334.

入库方式： OAI收割

来源：近代物理研究所

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