Mixture proportional hazards cure model with latent variables
文献类型：期刊论文
| 作者 | He, Haijin1; Han, Dongxiao2,3; Song, Xinyuan4; Sun, Liuquan5
|
| 刊名 | STATISTICS IN MEDICINE
 |
| 出版日期 | 2021-09-15 |
| 页码 | 15 |
| 关键词 | cure model factor analysis latent variables logistic regression proportional hazards model |
| ISSN号 | 0277-6715 |
| DOI | 10.1002/sim.9200 |
| 英文摘要 | A mixture proportional hazards cure model with latent variables is proposed. The proposed model assesses the effects of the observed and latent risk factors on the hazards of uncured subjects and the cure rate through a proportional hazards model and a logistic model, respectively. Factor analysis is employed to measure the latent variables through correlated multiple indicators. Maximum likelihood estimation is performed through a Gaussian quadratic technique that approximates the integration over the latent variables. A piecewise constant function is used for the unspecified baseline hazard of uncured subjects. The proposed method can be conveniently implemented by using SAS Proc NLMIXED. Simulation studies are conducted to evaluate the performance of the proposed approach. An application to a study concerning the risk factors of chronic kidney disease for type 2 diabetic patients is provided. |
| 资助项目 | Fundamental Research Funds for the Central Universities, Nankai University[9920200110] ; National Natural Science Foundation of China (NSFC)[11701387] ; Natural Science Foundation of Guangdong Province of China[2019A1515011917] ; Natural Science Foundation of Shenzhen[JCYJ20190808173603590] ; Research Grant Council of the HKSAR[14301918] ; Research Grant Council of the HKSAR[14302519] ; Chinese University of Hong Kong ; NSFC[11771431] ; NSFC[11690015] ; Key Laboratory of RCSDS, CAS[2008DP173182] |
| WOS研究方向 | Mathematical & Computational Biology ; Public, Environmental & Occupational Health ; Medical Informatics ; Research & Experimental Medicine ; Mathematics |
| 语种 | 英语 |
| WOS记录号 | WOS:000696099200001 |
| 出版者 | WILEY |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/59260]  |
| 专题 | 应用数学研究所 |
| 通讯作者 | Han, Dongxiao |
| 作者单位 | 1.Shenzhen Univ, Coll Math & Stat, Shenzhen, Peoples R China 2.Nankai Univ, Sch Stat & Data Sci, LPMC, Tianjin, Peoples R China 3.Nankai Univ, KLMDASR, Tianjin, Peoples R China 4.Chinese Univ Hong Kong, Dept Stat, Hong Kong, Peoples R China 5.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Haijin,Han, Dongxiao,Song, Xinyuan,et al. Mixture proportional hazards cure model with latent variables[J]. STATISTICS IN MEDICINE,2021:15. |
| APA | He, Haijin,Han, Dongxiao,Song, Xinyuan,&Sun, Liuquan.(2021).Mixture proportional hazards cure model with latent variables.STATISTICS IN MEDICINE,15. |
| MLA | He, Haijin,et al."Mixture proportional hazards cure model with latent variables".STATISTICS IN MEDICINE (2021):15. |
入库方式： OAI收割
来源：数学与系统科学研究院
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