中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Adjusted Log-rank Test with Double Inverse Weighting under Dependent Censoring

文献类型:期刊论文

作者Guo, Yi Min1,2; Zhou, Jie3; Sun, Liu Quan1,2
刊名ACTA MATHEMATICA SINICA-ENGLISH SERIES
出版日期2021-10-01
卷号37期号:10页码:1573-1585
关键词Adjusted log-rank test dependent censoring double inverse weighting survival data
ISSN号1439-8516
DOI10.1007/s10114-021-0050-1
英文摘要It is a common issue to compare treatment-specific survival and the weighted log-rank test is the most popular method for group comparison. However, in observational studies, treatments and censoring times are usually not independent, which invalidates the weighted log-rank tests. In this paper, we propose adjusted weighted log-rank tests in the presence of non-random treatment assignment and dependent censoring. A double-inverse weighted technique is developed to adjust the weighted log-rank tests. Specifically, inverse probabilities of treatment and censoring weighting are involved to balance the baseline treatment assignment and to overcome dependent censoring, respectively. We derive the asymptotic distribution of the proposed adjusted tests under the null hypothesis, and propose a method to obtain the critical values. Simulation studies show that the adjusted log-rank tests have correct sizes whereas the traditional weighted log-rank tests may fail in the presence of non-random treatment assignment and dependent censoring. An application to oropharyngeal carcinoma data from the Radiation Therapy Oncology Group is provided for illustration.
资助项目Beijing Municipal Education Commission[KM202010028017] ; National Natural Science Foundation of China[11771431] ; National Natural Science Foundation of China[11690015] ; Key Laboratory of RCSDS, CAS[2008DP173182] ; Academy for Multidisciplinary Studies of Capital Normal University
WOS研究方向Mathematics
语种英语
WOS记录号WOS:000707010700008
出版者SPRINGER HEIDELBERG
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/59380]  
专题应用数学研究所
通讯作者Zhou, Jie
作者单位1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Capital Normal Univ, Sch Math Sci, Beijing 100048, Peoples R China
推荐引用方式
GB/T 7714
Guo, Yi Min,Zhou, Jie,Sun, Liu Quan. Adjusted Log-rank Test with Double Inverse Weighting under Dependent Censoring[J]. ACTA MATHEMATICA SINICA-ENGLISH SERIES,2021,37(10):1573-1585.
APA Guo, Yi Min,Zhou, Jie,&Sun, Liu Quan.(2021).Adjusted Log-rank Test with Double Inverse Weighting under Dependent Censoring.ACTA MATHEMATICA SINICA-ENGLISH SERIES,37(10),1573-1585.
MLA Guo, Yi Min,et al."Adjusted Log-rank Test with Double Inverse Weighting under Dependent Censoring".ACTA MATHEMATICA SINICA-ENGLISH SERIES 37.10(2021):1573-1585.

入库方式: OAI收割

来源:数学与系统科学研究院

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