Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption
文献类型：期刊论文
| 作者 | Wang JL(王九令) ; Wei YJ(魏宇杰); Shi XH(施兴华); Gao HJ
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2013-09-28 |
| 卷号 | 3期号:36页码:15776-15782 |
| 通讯作者邮箱 | shixh@imech.ac.cn |
| 关键词 | Carbon Nanotubes Graphene Nanosheets Lipid-Bilayers Coarse-Grained Model Molecular-Dynamics Hydrophobicity Surface Absorption Oxidation Bio Medical DiagnosticsCarbon Nanotubes Graphene Nanosheets Lipid-Bilayers Coarse-Grained Model Molecular-Dynamics Hydrophobicity Surface Absorption Oxidation Bio Medical Diagnostics |
| ISSN号 | 2046-2069 |
| 产权排序 | [Wang, Jiuling; Wei, Yujie; Shi, Xinghua] Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China; [Gao, Huajian] Brown Univ, Sch Engn, Providence, RI 02912 USA |
| 通讯作者 | Shi, XH (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China. |
| 合作状况 | 国际 |
| 中文摘要 | Coarse grained molecular dynamics simulations are conducted to study the interaction of graphene nanosheets with a lipid bilayer, focusing on the effects of graphene thicknesses (single/multi-layered graphene), oxidation and surface absorption by lipid molecules. The results show that a hydrophobic corner of graphene can pierce into the bilayer, while different oxidations of the nanosheets affect their final equilibrium configurations in the bilayer: lying across or within the hydrophobic core of the bilayer. The underlying mechanism is clarified by calculating the energy barrier for graphene piercing into the bilayer. Our studies provide fundamental guidance towards understanding how graphene enters cells, which is important for biomedical diagnostics and therapies, and for managing health impacts following occupational or environmental exposure. |
| 学科主题 | 固体力学 |
| 分类号 | 二类/Q2 |
| 收录类别 | SCI ; EI |
| 资助信息 | National Natural Science Foundation of China (NSFC) [11272327]; National Science Foundation (NSF) [CMMI-1028530]; Supercomputing Center of Chinese Academy of Sciences (SCCAS) |
| 原文出处 | http://dx.doi.org/10.1039/c3ra40392k |
| 语种 | 英语 |
| WOS记录号 | WOS:000323271700037 |
| 公开日期 | 2013-09-27 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/47462]  |
| 专题 | 力学研究所_非线性力学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Wang JL,Wei YJ,Shi XH,et al. Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption[J]. RSC ADVANCES,2013,3(36):15776-15782. |
| APA | Wang JL,Wei YJ,Shi XH,&Gao HJ.(2013).Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption.RSC ADVANCES,3(36),15776-15782. |
| MLA | Wang JL,et al."Cellular entry of graphene nanosheets: The role of thickness, oxidation and surface adsorption".RSC ADVANCES 3.36(2013):15776-15782. |
入库方式： OAI收割
来源：力学研究所
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