Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense
文献类型：期刊论文
| 作者 | Hu,Yi-Kao; Wang,Li ; Wang,Ji-Hua; Li,Meng-Jia; Li,Feng; Yang,Jing; Zhao,Yong
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| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2021 |
| 卷号 | 35期号:24页码:5948-5953 |
| 关键词 | Syzygium samarangense resorcinol derivatives alpha-glucosidase inhibitory activity TRITERPENOIDS LEAVES |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786419.2020.1805606 |
| 英文摘要 | Nine resorcinol derivatives including two new ones, 5-[(8Z,11Z,14Z)-nonadeca-8,11,14-trienyl] resorcinol (1) and 5-[(8Z,11Z,14E)-heptadeca-8,11,14-trienyl] resorcinol (2), were isolated from the leaves ofSyzygium samarangense. The new structures were elucidated by means of extensive spectroscopic techniques including interpretation of 1D and 2D NMR spectra. Among them, compounds3,4,6 and 7 exhibited significant alpha-glucosidase inhibitory activities with IC50 of 3.16, 3.16, 2.34 and 0.99 mu M, respectively. This finding provides evidence that resorcinol derivatives with long aliphatic chain function as new promising antidiabetic alternatives.[GRAPHICS]. |
| WOS记录号 | WOS:000558965200001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73010]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Yunnan Normal Univ, Coll Chem & Chem Engn, Kunming, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu,Yi-Kao,Wang,Li,Wang,Ji-Hua,et al. Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense[J]. NATURAL PRODUCT RESEARCH,2021,35(24):5948-5953. |
| APA | Hu,Yi-Kao.,Wang,Li.,Wang,Ji-Hua.,Li,Meng-Jia.,Li,Feng.,...&Zhao,Yong.(2021).Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense.NATURAL PRODUCT RESEARCH,35(24),5948-5953. |
| MLA | Hu,Yi-Kao,et al."Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense".NATURAL PRODUCT RESEARCH 35.24(2021):5948-5953. |
入库方式： OAI收割
来源：昆明植物研究所
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