Phyllanacidins A-C, three new cleistanthane diterpenoids from Phyllanthus acidus and their cytotoxicities
文献类型：期刊论文
| 作者 | Geng,Hui-Chun; Zhu,Hong-Tao; Wang,Dong ; Yang,Wei-Nong; Yang,Chong-Ren; Zhang,Ying-Jun
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2021 |
| 卷号 | 148页码:104793 |
| 关键词 | Phyllanthus acidus Cleistanthane diterpenoids Cytotoxicity CASSANE |
| ISSN号 | 0367-326X |
| DOI | 10.1016/j.fitote.2020.104793 |
| 英文摘要 | Phytochemical investigation on the nonpolar extracts of P. acidus leaves afforded three new cleistanthane diterpenoids, named phyllanacidins A-C (1-3) 5 in addition to three known ones (4-6). Among them, compounds 2 and 3 represent the first examples of 17-nor cleistanthane diterpenoids. Their structures including absolute configurations were elucidated on the basis of extensive spectroscopic data and single crystal X-ray diffraction analysis. All the isolated cleistanthane diterpenoids were evaluated for their cytotoxic activities against five human cancer cell lines. Compounds 4-6 exhibited moderate cytotoxicity with IC50 values ranging from 16.11 to 30.82 mu M. |
| WOS记录号 | WOS:000604579800007 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73042]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.[Geng, Hui-Chun 3.Zhu, Hong-Tao 4.Wang, Dong 5.Yang, Chong-Ren 6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 7.Yunnan Acad Agr Sci, Qual Standardizing & Testing Technol Inst, Kunming 650223, Yunnan, Peoples R China 8.Yunnan Xinxing Greening Engn Co, Kunming 650228, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Geng,Hui-Chun,Zhu,Hong-Tao,Wang,Dong,et al. Phyllanacidins A-C, three new cleistanthane diterpenoids from Phyllanthus acidus and their cytotoxicities[J]. FITOTERAPIA,2021,148:104793. |
| APA | Geng,Hui-Chun,Zhu,Hong-Tao,Wang,Dong,Yang,Wei-Nong,Yang,Chong-Ren,&Zhang,Ying-Jun.(2021).Phyllanacidins A-C, three new cleistanthane diterpenoids from Phyllanthus acidus and their cytotoxicities.FITOTERAPIA,148,104793. |
| MLA | Geng,Hui-Chun,et al."Phyllanacidins A-C, three new cleistanthane diterpenoids from Phyllanthus acidus and their cytotoxicities".FITOTERAPIA 148(2021):104793. |
入库方式： OAI收割
来源：昆明植物研究所
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