Anti-Food Allergic Alkaloids from the Lotus Seed Pot
文献类型：期刊论文
| 作者 | Cao,Tuan-Wu; Xie,Chun-Lan; Chen,Chao-Qun; He,Zhi-Hui; Yan,Qing-Xiang; Xu,Gang ; Yang,Xian-Wen
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| 刊名 | CHEMISTRY & BIODIVERSITY
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| 出版日期 | 2021 |
| 卷号 | 18期号:12页码:e2100770 |
| 关键词 | Nelumbo nucifera lotus seed pod alkaloids anti-food allergy APORPHINE ALKALOIDS NELUMBO-NUCIFERA ANTIOXIDANT LEAVES |
| ISSN号 | 1612-1872 |
| DOI | 10.1002/cbdv.202100770 |
| 英文摘要 | Lotus seed pod (LSP) has been used as traditional herbal cuisine to modulate immunity. From the AcOEt-soluble extract of LSP, one new aporphine alkaloid, N-[2-(2H-phenanthro[3,4-d][1,3]dioxol-5-yl)ethyl]acetamide (nelunucine A, 1) was obtained along with 19 known ones. Their structures were established by detailed analysis of the 1D-, 2D-NMR, and HR-ESI-MS data. N-Nornuciferine (9) and lirinidine (10) showed potent in vitro anti-food allergic activity with IC50 values of 40.0 and 55.4 mu M, respectively, compared to 91.4 mu M for loratadine, the positive control. |
| WOS记录号 | WOS:000716555700001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73144]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 2.[Chen, Chao-Qun 3.Yan, Qing-Xiang 4.He, Zhi-Hui 5.Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 6.Yangtze Normal Univ, Lab Nat Med Res & Dev Wuling Mt, Sch Chem & Chem Engn, Fuling 408100, Peoples R China 7.[Xie, Chun-Lan 8.Minist Nat Resources, Inst Oceanog 3, Key Lab Marine Biogenet Resources, 184 Daxue Rd, Xiamen 361005, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao,Tuan-Wu,Xie,Chun-Lan,Chen,Chao-Qun,et al. Anti-Food Allergic Alkaloids from the Lotus Seed Pot[J]. CHEMISTRY & BIODIVERSITY,2021,18(12):e2100770. |
| APA | Cao,Tuan-Wu.,Xie,Chun-Lan.,Chen,Chao-Qun.,He,Zhi-Hui.,Yan,Qing-Xiang.,...&Yang,Xian-Wen.(2021).Anti-Food Allergic Alkaloids from the Lotus Seed Pot.CHEMISTRY & BIODIVERSITY,18(12),e2100770. |
| MLA | Cao,Tuan-Wu,et al."Anti-Food Allergic Alkaloids from the Lotus Seed Pot".CHEMISTRY & BIODIVERSITY 18.12(2021):e2100770. |
入库方式： OAI收割
来源：昆明植物研究所
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