Chemical Synthesis of the Nucleoside Antibiotic Capuramycin
文献类型:期刊论文
作者 | Xiao,Guozhi; He,Haiqing |
刊名 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY |
出版日期 | 2021 |
卷号 | 2021期号:26页码:3681-3689 |
ISSN号 | 1434-193X |
关键词 | Capuramycin Chemical synthesis Glycosyl ortho-(1-phenylvinyl)benzoates One-pot glycosylation Tuberculosis DRUG-RESISTANT TUBERCULOSIS GLUTAMIC-ACID-DERIVATIVES MULTIDRUG-RESISTANT PROTECTING GROUPS IN-VITRO GLYCOSYLATION INHIBITORS ALCOHOLS ANALOGS OXIDATION |
DOI | 10.1002/ejoc.202100613 |
英文摘要 | Capuramycin is an important lead nucleoside antibiotic for the development of new therapeutic agents against the multidrug-resistant Mycobacterium tuberculosis infections. Due to the poor accessibilities, the heterogeneous issues and difficulties in the modification of capuramycin at the specific positions, in-depth studies on the structure-activity relationships (SAR) of capuramycin are hampered. Chemical synthesis is a reliable and effective method to provide capuramycin and its analogues. Thus far, only four different synthetic routes toward capuramycin have been reported. Herein, we provide a comprehensive review on the chemical synthesis of capuramycin. |
WOS记录号 | WOS:000674246400006 |
源URL | [http://ir.kib.ac.cn/handle/151853/73190] |
专题 | 中国科学院昆明植物研究所 |
作者单位 | Univ Chinese Acad Sci, Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Xiao,Guozhi,He,Haiqing. Chemical Synthesis of the Nucleoside Antibiotic Capuramycin[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2021,2021(26):3681-3689. |
APA | Xiao,Guozhi,&He,Haiqing.(2021).Chemical Synthesis of the Nucleoside Antibiotic Capuramycin.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2021(26),3681-3689. |
MLA | Xiao,Guozhi,et al."Chemical Synthesis of the Nucleoside Antibiotic Capuramycin".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2021.26(2021):3681-3689. |
入库方式: OAI收割
来源:昆明植物研究所
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