Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith
文献类型:期刊论文
作者 | Nie,Wei; Ding,Lin-Fen; Lei,Tie; Pan,Zheng-Hong; Song,Liu-Dong; Wu,Xing-De; Zhao,Qin-Shi |
刊名 | TETRAHEDRON LETTERS
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出版日期 | 2021 |
卷号 | 70页码:153022 |
关键词 | Illicium lanceolatum A. C. Smith Seco-prezizaane sesquiterpenoid Neurotrophic activity Neuroprotective effect NEUROTROPHIC ACTIVITY PERICARPS ANISATIN |
ISSN号 | 0040-4039 |
DOI | 10.1016/j.tetlet.2021.153022 |
英文摘要 | A unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic skeleton, illilanceolide A (1), and two rare 10,14-cycloseco-prezizaane sesquiterpenoids, 2-oxo-6-dehydroxyneoanisatinic acid (2) and 3,4-anhydro-2-oxo-6-dehydroxyneoanisatinic acid (3), together with two known sesquiterpenoids, were isolated from the fruits of Illicium lanceolatum. Their structures and absolute configurations were elucidated on the basis of extensive H-1, C-13, and 2D NMR, and HRESIMS data, as well as single-crystal X-ray diffraction analysis. Compounds 2-4 enhanced the neurite outgrowth of NGF-mediated PC12 cells at a concentration of 10 mu M with differentiation rates of 13.33%, 10.90%, and 11.76%, respectively. Moreover, compounds 2-4 were found to exhibit moderate neuroprotective effect against MPP+-induced PC12 cell damage. (C) 2021 Elsevier Ltd. All rights reserved. |
WOS记录号 | WOS:000641047500024 |
源URL | [http://ir.kib.ac.cn/handle/151853/73204] ![]() |
专题 | 中国科学院昆明植物研究所 |
作者单位 | 1.Chinese Acad Sci, Guangxi Inst Bot, Guangxi Key Lab Funct Phytochem Res & Utilizat, Guilin 541006, Peoples R China 2.[Nie, Wei 3.Ding, Lin-Fen 4.Lei, Tie 5.Wu, Xing-De 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 7.Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China 8.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Nie,Wei,Ding,Lin-Fen,Lei,Tie,et al. Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith[J]. TETRAHEDRON LETTERS,2021,70:153022. |
APA | Nie,Wei.,Ding,Lin-Fen.,Lei,Tie.,Pan,Zheng-Hong.,Song,Liu-Dong.,...&Zhao,Qin-Shi.(2021).Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith.TETRAHEDRON LETTERS,70,153022. |
MLA | Nie,Wei,et al."Illilanceolide A, a unique seco-prezizaane sesquiterpenoid with 5/5/6 tricyclic scaffold from the fruits of Illicium lanceolatum A. C. Smith".TETRAHEDRON LETTERS 70(2021):153022. |
入库方式: OAI收割
来源:昆明植物研究所
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