Carbon dots derived from Fusobacterium nucleatum for intracellular determination of Fe3+ and bioimaging both in vitro and in vivo
文献类型：期刊论文
| 作者 | Liu,Lijuan; Zhang,Shengting; Zheng,Xiaodan; Li,Hongmei; Chen,Qi; Qin,Kunhao; Ding,Yafang; Wei,Yunlin |
| 刊名 | ANALYTICAL METHODS
 |
| 出版日期 | 2021 |
| 卷号 | 13期号:9页码:1121-1131 |
| ISSN号 | 1759-9660 |
| DOI | 10.1039/d1ay00020a |
| 英文摘要 | Intracellular Fe3+ amount is one of the critical determinants of human health. The development of simple and effective probes for the quantitative detection of Fe(3+)in vivo is of great significance for the early diagnosis of disease or disorder associated with iron deficiency or overload. In this study, remarkable carbon dots, which can serve as a biosensor for efficient intracellular Fe3+ detection, were synthesized by hydrothermal carbonization of Fusobacterium nucleatum, an anaerobic bacterium. The achieved F. nucleatum-carbon dots (Fn-CDs) possessed the features of strong fluorescence, high stability and excellent biocompatibility. The obtained Fn-CDs could easily internalize into both plant cells and human cells with excellent ability for cell tracking and biomedical labeling. The fluorescence of Fn-CDs could still remain for another 24 hours after penetrating into cells. Furthermore, the fluorescent Fn-CDs were very sensitive to the presence of Fe3+ ions even in cells, exhibiting great promising applications in in vivo detection of Fe3+ ions. In addition, the Fn-CDs posed no harm to the mice, being circulated and excreted within a short time, making the Fn-CDs an excellent candidate for bioimaging and biosensing in vivo. |
| WOS记录号 | WOS:000627499900003 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73221]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming 650500, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Yunnan Univ, Dept Hematol, Peoples Hosp Yunnan Prov 2, Affiliated Hosp, Kunming 650021, Yunnan, Peoples R China 4.Jinan Univ, Shenzhen Inst Resp Dis, Clin Med Coll 2, Shenzhen Peoples Hosp, Shenzhen 518020, Peoples R China 5.Yunnan Minzu Univ, Dept Educ, Kunming 650500, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu,Lijuan,Zhang,Shengting,Zheng,Xiaodan,et al. Carbon dots derived from Fusobacterium nucleatum for intracellular determination of Fe3+ and bioimaging both in vitro and in vivo[J]. ANALYTICAL METHODS,2021,13(9):1121-1131. |
| APA | Liu,Lijuan.,Zhang,Shengting.,Zheng,Xiaodan.,Li,Hongmei.,Chen,Qi.,...&Wei,Yunlin.(2021).Carbon dots derived from Fusobacterium nucleatum for intracellular determination of Fe3+ and bioimaging both in vitro and in vivo.ANALYTICAL METHODS,13(9),1121-1131. |
| MLA | Liu,Lijuan,et al."Carbon dots derived from Fusobacterium nucleatum for intracellular determination of Fe3+ and bioimaging both in vitro and in vivo".ANALYTICAL METHODS 13.9(2021):1121-1131. |
入库方式： OAI收割
来源：昆明植物研究所
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