A new antimicrobial nor-friedelane-type triterpenoid and other constituents from Plectranthus glandulosus Hook. f. (Lamiaceae)
文献类型：期刊论文
| 作者 | Tedonkeu,Alex Tchinda; Tamokou,Jean-De-Dieu; Mpetga,James D. Simo; Nzogong,Raissa Tioyem; Kengne,Irene Chinda; Hao,Xiao-Jiang ; Tene,Mathieu
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| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2021 |
| 关键词 | Plectranthus glandulosus Lamiaceae triterpenoids nor-friedelane antimicrobial activity STEM BARK ACID FLAVONE EXTRACT PLANT |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786419.2021.1999946 |
| 英文摘要 | Chemical investigation of the ethanol extract from the whole plant of Plectranthus glandulosus led to the isolation of a new nor-triterpenoid (1) along with seventeen known compounds (2-18) including seven triterpenoids, nine flavonoids and one steroid. Their structures were established on the basis of 1D- and 2D-NMR, IR, and MS experiments, and by comparison of their spectroscopic data with those of similar compounds reported in the literature. The EtOH extract and some isolated triterpenoids (1-4 and 13) were subjected to in vitro antimicrobial assays against a panel of pathogenic microorganisms, including Gram-positive and Gram-negative bacteria, and fungi using broth microdilution method. The EtOH extract displayed moderate activity (MIC = 512 mu g/mL) against Staphylococcus aureus MSSA1, Shigella flexneri SDINT and Cryptococcus neoformans H99. Compounds 1, 4 and 13 showed the most potent antimicrobial effect with MICs of 32-256 mu g/mL. |
| WOS记录号 | WOS:000714260500001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73279]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China 2.[Tamokou, Jean-De-Dieu 3.Mpetga, James D. Simo 4.Univ Dschang, Fac Sci, Dept Chem, Nat Prod Chem Res Unit, Dschang, Cameroon 5.Nzogong, Raissa Tioyem 6.Univ Dschang, Fac Sci, Dept Biochem, Res Unit Microbiol & Antimicrobial Subst, Dschang, Cameroon 7.[Tedonkeu, Alex Tchinda |
| 推荐引用方式 GB/T 7714 | Tedonkeu,Alex Tchinda,Tamokou,Jean-De-Dieu,Mpetga,James D. Simo,et al. A new antimicrobial nor-friedelane-type triterpenoid and other constituents from Plectranthus glandulosus Hook. f. (Lamiaceae)[J]. NATURAL PRODUCT RESEARCH,2021. |
| APA | Tedonkeu,Alex Tchinda.,Tamokou,Jean-De-Dieu.,Mpetga,James D. Simo.,Nzogong,Raissa Tioyem.,Kengne,Irene Chinda.,...&Tene,Mathieu.(2021).A new antimicrobial nor-friedelane-type triterpenoid and other constituents from Plectranthus glandulosus Hook. f. (Lamiaceae).NATURAL PRODUCT RESEARCH. |
| MLA | Tedonkeu,Alex Tchinda,et al."A new antimicrobial nor-friedelane-type triterpenoid and other constituents from Plectranthus glandulosus Hook. f. (Lamiaceae)".NATURAL PRODUCT RESEARCH (2021). |
入库方式： OAI收割
来源：昆明植物研究所
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