Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China
文献类型：期刊论文
| 作者 | Wang,Bin ; Hu,Kun; Li,Xiao-Nian; Sun,Han-Dong; Qin,Hong-Bo; Puno,Pema-Tenzin
|
| 刊名 | BIOORGANIC CHEMISTRY
 |
| 出版日期 | 2021 |
| 卷号 | 110页码:104785 |
| 关键词 | Schisandra neglecta 16 17-secopreschisanartane-type schinortriterpenoids Schisdilactones K?U Quantum chemical calculation Neuroprotective activity DIBENZOCYCLOOCTADIENE LIGNANS NORTRITERPENOIDS CHINENSIS STEMS 7,8-SECOLIGNANS TRITERPENOIDS |
| ISSN号 | 0045-2068 |
| DOI | 10.1016/j.bioorg.2021.104785 |
| 英文摘要 | Schisdilactones K?U (1?11), a series of previously unreported 16,17-secopreschisanartane-type schinortriterpenoids (SNTs), were isolated from the leaves and stems of Schisandra neglecta A. C. Smith. Their structures were mainly established through analysis of their spectroscopic data. Besides, schisdilactones K (1), O (5) and R (8) were confirmed by single-crystal X-ray crystallographic analysis, and the configurations of schisdilactones T and U (10 and 11) were elucidated via quantum chemical calculation of their NMR chemical shifts and electronic circular dichroism (ECD) spectra. Schisdilactones L?S (2?8) and U (11) were found to exhibit moderate protective activities against corticosterone-induced apoptosis of PC12 cells at 20 ?M, with cell viability in the range of 62.95?66.97%. |
| WOS记录号 | WOS:000744355400004 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73350]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochemistry & Plant Resources We, Kunming, Yunnan, Peoples R China 3.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang,Bin,Hu,Kun,Li,Xiao-Nian,et al. Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China[J]. BIOORGANIC CHEMISTRY,2021,110:104785. |
| APA | Wang,Bin,Hu,Kun,Li,Xiao-Nian,Sun,Han-Dong,Qin,Hong-Bo,&Puno,Pema-Tenzin.(2021).Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China.BIOORGANIC CHEMISTRY,110,104785. |
| MLA | Wang,Bin,et al."Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China".BIOORGANIC CHEMISTRY 110(2021):104785. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。