A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?
文献类型：期刊论文
| 作者 | Gou,Leilei; Yue,Grace Gar-Lee; Puno,Pema Tenzin; Lau,Clara Bik-San |
| 刊名 | PHARMACOLOGICAL RESEARCH
 |
| 出版日期 | 2021 |
| 卷号 | 164页码:105321 |
| 关键词 | Breast cancer Mast cell Macrophage Natural products Herbs Extracts TUMOR-ASSOCIATED MACROPHAGES NF-KAPPA-B MEDIATED ALLERGIC REACTIONS PRO-INFLAMMATORY CYTOKINES ANTIINFLAMMATORY ACTIVITY ATOPIC-DERMATITIS UMBROSA ROOT TNF-ALPHA IN-VIVO C-KIT |
| ISSN号 | 1043-6618 |
| DOI | 10.1016/j.phrs.2020.105321 |
| 英文摘要 | Breast cancer is an inflammation-related cancer whose tumor microenvironment is largely infiltrated by inflammatory cells. These inflammatory cells including mast cells and macrophages have been elucidated to be vital participants in breast tumor proliferation, survival, invasion and migration. However, the functions of mast cells and macrophages in breast cancer are quite distinct based on recent data. Mast cells exhibit both anti-tumoral and pro-tumoral functions on breast cancer, while high number of tumor-associated macrophages (TAMs) are strongly correlated with poor prognosis and higher risk of distant metastasis in breast cancer patients. Besides, many natural products/extracts have been reported to regulate mast cells and macrophages. In this review, the roles of mast cells and macrophages play in breast cancer are discussed and a summary of those natural products/herbs regulating the functions of mast cells or macrophages is also presented. |
| WOS记录号 | WOS:000615153300009 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73366]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Univ Hong Kong, State Key Lab Res Bioact & Clin Applicat Med Plan, Shatin, Hksar, Peoples R China 4.Chinese Univ Hong Kong, Inst Chinese Med, Shatin, Hksar, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gou,Leilei,Yue,Grace Gar-Lee,Puno,Pema Tenzin,et al. A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?[J]. PHARMACOLOGICAL RESEARCH,2021,164:105321. |
| APA | Gou,Leilei,Yue,Grace Gar-Lee,Puno,Pema Tenzin,&Lau,Clara Bik-San.(2021).A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?.PHARMACOLOGICAL RESEARCH,164,105321. |
| MLA | Gou,Leilei,et al."A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?".PHARMACOLOGICAL RESEARCH 164(2021):105321. |
入库方式： OAI收割
来源：昆明植物研究所
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