New limonoids and quinolone alkaloids with cytotoxic and anti-platelet aggregation activities from Evodia rutaecarpa (Juss.) Benth
文献类型：期刊论文
| 作者 | Qin,Jing; Liao,Chao-Nan; Chen,Wei-wei; Li,Hong-you; Su,Jia; Wu,Xing-De; He,Jiang-bo; Zhang,Gao-hong |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2021 |
| 卷号 | 152页码:104875 |
| 关键词 | Limonoid Quinolone alkaloid Cytotoxic activity Anti-platelet aggregation Evodia rutaecarpa (Juss ) Benth FRUITS |
| ISSN号 | 0367-326X |
| DOI | 10.1016/j.fitote.2021.104875 |
| 英文摘要 | One new limonoid, named 19-hydroxy methyl isoobacunoate diosphenol (1); one new degraded limonoid, named 9 alpha-methoxyl dictamdiol (9); two new quinolone alkaloids, 1-methyl-3-[(7E,9E,12Z)-7,9,12-pentadecadienyl]-4(1H)-quinolone (11) and 1-methyl-3-[(7E,9E,11E)-7,9,11-pentadecadienyl]-4(1H)-quinolone (12), along with eight known compounds, evodol (2), 7 beta-acetoxy-5-epilimonin (3), rutaevine (4), 6 beta-acetoxy-5-epilimonin (5), limonin (6), obacunone (7), clauemargine L (8), hiiranlactone E (10) were isolated from the fruits of Evodia rutaecarpa (Juss.) Benth.. Structures of the four new compounds were elucidated on the basis of extensive spectroscopic techniques, including 1D and 2D NMR techniques. Compounds 3, 5, 9, 11 and 12 showed obviously cytotoxic activity against six human tumor lines, while compounds 11, 12 displayed anti-platelet aggregation induced by ADP at 50 mu M and 100 mu M. |
| WOS记录号 | WOS:000663829000012 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73649]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Kunming Univ, Sch Med, Kunming, Yunnan, Peoples R China 2.[Su, Jia 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China 4.Liao, Chao-Nan 5.Chen, Wei-wei 6.Li, Hong-you 7.He, Jiang-bo 8.[Qin, Jing |
| 推荐引用方式 GB/T 7714 | Qin,Jing,Liao,Chao-Nan,Chen,Wei-wei,et al. New limonoids and quinolone alkaloids with cytotoxic and anti-platelet aggregation activities from Evodia rutaecarpa (Juss.) Benth[J]. FITOTERAPIA,2021,152:104875. |
| APA | Qin,Jing.,Liao,Chao-Nan.,Chen,Wei-wei.,Li,Hong-you.,Su,Jia.,...&Zhang,Gao-hong.(2021).New limonoids and quinolone alkaloids with cytotoxic and anti-platelet aggregation activities from Evodia rutaecarpa (Juss.) Benth.FITOTERAPIA,152,104875. |
| MLA | Qin,Jing,et al."New limonoids and quinolone alkaloids with cytotoxic and anti-platelet aggregation activities from Evodia rutaecarpa (Juss.) Benth".FITOTERAPIA 152(2021):104875. |
入库方式： OAI收割
来源：昆明植物研究所
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