Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells
文献类型：期刊论文
| 作者 | Song,Ying-Ying; Jiang,Jian-Bing; Yan,Yong-Ming; Cheng,Yong-Xian |
| 刊名 | BIOORGANIC CHEMISTRY
 |
| 出版日期 | 2021 |
| 卷号 | 114页码:105067 |
| 关键词 | Belamcanda chinensis Triterpenoids TGF-beta 1 Kidney proximal tubular cells TGF-BETA TRITERPENOIDS CONSTITUENTS |
| ISSN号 | 0045-2068 |
| DOI | 10.1016/j.bioorg.2021.105067 |
| 英文摘要 | Belamcandaoids A-N (1-14), fourteen new triterpenoids were isolated from the seeds of Belamcanda chinensis. Their structures including absolute configurations were assigned by using spectroscopic, computational, and crystallographic methods. All the compounds except 1 and 2 are 3,4-seco-triterpenoids belonging to fernane type. Biological evaluation results indicated that 3 and 13 could reduce fibronectin and collagen I expression respectively in TGF-beta 1 induced kidney proximal tubular cells. |
| WOS记录号 | WOS:000689510400003 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73741]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yan, Yong-Ming 3.Shenzhen Univ, Sch Pharmaceut Sci, Inst Inheritance Based Innovat Chinese Med, Hlth Sci Ctr, Shenzhen 518060, Peoples R China 4.Hanshan Normal Univ, Sch Life Sci & Food Engn, Guangdong Key Lab Funct Subst Med Edible Resource, Chaozhou 521041, Peoples R China 5.[Jiang, Jian-Bing |
| 推荐引用方式 GB/T 7714 | Song,Ying-Ying,Jiang,Jian-Bing,Yan,Yong-Ming,et al. Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells[J]. BIOORGANIC CHEMISTRY,2021,114:105067. |
| APA | Song,Ying-Ying,Jiang,Jian-Bing,Yan,Yong-Ming,&Cheng,Yong-Xian.(2021).Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells.BIOORGANIC CHEMISTRY,114,105067. |
| MLA | Song,Ying-Ying,et al."Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells".BIOORGANIC CHEMISTRY 114(2021):105067. |
入库方式： OAI收割
来源：昆明植物研究所
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