中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Five new secondary metabolites from the fungus Phomopsis asparagi

文献类型:期刊论文

作者Zhou,Peng; Yan,Shan; Lu,Yuanyuan; Li,Xiao-Nian; Zhang,Mi; Li,Qin; Chen,Xia; Wang,Jianping; Zhu,Hucheng; Chen,Chunmei
刊名FITOTERAPIA
出版日期2021
卷号150页码:104840
关键词Phomopsis asparagi Diphenylcyclopentenone Diketopiperazine A-glucosidase inhibition ASPERGILLUS-FUMIGATUS STEM BLIGHT DERIVATIVES INHIBITORS
ISSN号0367-326X
DOI10.1016/j.fitote.2021.104840
英文摘要Five new compounds, including a pair of diphenylcyclopentenone enantiomers (+/-)-phomopsisin A (1), a sesquiterpenoid 15-hydroxylithocarin A (2), a new diketopiperazine alkaloid prenylcyclotryprostatin A (3) and 7hydroxy-cis-L(- )-3,6-dibenzyl-2,5-dioxopiperazine (6), along with five known compounds were isolated from the fungus Phomopsis asparagi. Their structures were elucidated on the basis of spectroscopic analyses (1D and 2D NMR), theoretical electronic circular dichroism (ECD) calculation, modified Mosher's method, and X-ray crystallography. The racemates of (+/-)-phomopsisin A showed inhibition on alpha-glucosidase with IC50 of 30.07 +/- 0.75 mu M (positive control acarbose, 121 +/- 2.7 mu M).
WOS记录号WOS:000661456300008
源URL[http://ir.kib.ac.cn/handle/151853/73767]  
专题中国科学院昆明植物研究所
作者单位1.Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei, Peoples R China
2.Huazhong Univ Sci & Technol, Tongji Med Coll, Maternal & Child Hlth Hosp Hubei Prov, Wuhan 430070, Hubei, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Zhou,Peng,Yan,Shan,Lu,Yuanyuan,et al. Five new secondary metabolites from the fungus Phomopsis asparagi[J]. FITOTERAPIA,2021,150:104840.
APA Zhou,Peng.,Yan,Shan.,Lu,Yuanyuan.,Li,Xiao-Nian.,Zhang,Mi.,...&Zhang,Yonghui.(2021).Five new secondary metabolites from the fungus Phomopsis asparagi.FITOTERAPIA,150,104840.
MLA Zhou,Peng,et al."Five new secondary metabolites from the fungus Phomopsis asparagi".FITOTERAPIA 150(2021):104840.

入库方式: OAI收割

来源:昆明植物研究所

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