Five new secondary metabolites from the fungus Phomopsis asparagi
文献类型：期刊论文
| 作者 | Zhou,Peng; Yan,Shan; Lu,Yuanyuan; Li,Xiao-Nian; Zhang,Mi; Li,Qin; Chen,Xia; Wang,Jianping; Zhu,Hucheng; Chen,Chunmei |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2021 |
| 卷号 | 150页码:104840 |
| 关键词 | Phomopsis asparagi Diphenylcyclopentenone Diketopiperazine A-glucosidase inhibition ASPERGILLUS-FUMIGATUS STEM BLIGHT DERIVATIVES INHIBITORS |
| ISSN号 | 0367-326X |
| DOI | 10.1016/j.fitote.2021.104840 |
| 英文摘要 | Five new compounds, including a pair of diphenylcyclopentenone enantiomers (+/-)-phomopsisin A (1), a sesquiterpenoid 15-hydroxylithocarin A (2), a new diketopiperazine alkaloid prenylcyclotryprostatin A (3) and 7hydroxy-cis-L(- )-3,6-dibenzyl-2,5-dioxopiperazine (6), along with five known compounds were isolated from the fungus Phomopsis asparagi. Their structures were elucidated on the basis of spectroscopic analyses (1D and 2D NMR), theoretical electronic circular dichroism (ECD) calculation, modified Mosher's method, and X-ray crystallography. The racemates of (+/-)-phomopsisin A showed inhibition on alpha-glucosidase with IC50 of 30.07 +/- 0.75 mu M (positive control acarbose, 121 +/- 2.7 mu M). |
| WOS记录号 | WOS:000661456300008 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/73767]  |
| 专题 | 中国科学院昆明植物研究所 |
| 作者单位 | 1.Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei, Peoples R China 2.Huazhong Univ Sci & Technol, Tongji Med Coll, Maternal & Child Hlth Hosp Hubei Prov, Wuhan 430070, Hubei, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou,Peng,Yan,Shan,Lu,Yuanyuan,et al. Five new secondary metabolites from the fungus Phomopsis asparagi[J]. FITOTERAPIA,2021,150:104840. |
| APA | Zhou,Peng.,Yan,Shan.,Lu,Yuanyuan.,Li,Xiao-Nian.,Zhang,Mi.,...&Zhang,Yonghui.(2021).Five new secondary metabolites from the fungus Phomopsis asparagi.FITOTERAPIA,150,104840. |
| MLA | Zhou,Peng,et al."Five new secondary metabolites from the fungus Phomopsis asparagi".FITOTERAPIA 150(2021):104840. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。