Surface engineered bimetallic gold/silver nanoclusters for in situ imaging of mercury ions in living organisms
文献类型：期刊论文
| 作者 | Wang, Jianping3; Wang, Wang3; Yang, Linlin1,2; Zhao, Jun1; Han, Guangmei1; Yu, Xiaoping3; ShenTu, Xuping3; Ye, Zihong3 |
| 刊名 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY
 |
| 出版日期 | 2022-04-21 |
| ISSN号 | 1618-2642 |
| 关键词 | Bimetallic nanoclusters Red emission Hg2+ In situ Bioimaging |
| DOI | 10.1007/s00216-022-04076-6 |
| 通讯作者 | Yang, Linlin(llyang@iim.ac.cn) ; Ye, Zihong(zhye@cjlu.edu.cn) |
| 英文摘要 | Chemical sensing for the sensitive and reliable detection of mercury(II) ions (Hg2+) is of great importance in environmental protection, food safety, and biomedical applications. Due to the bio-enrichment property of Hg2+ in organisms, it is particularly meaningful to develop an effective tool that can in situ and rapidly monitor the level of Hg2+ in living organisms. In this work, we report ligand functionalized gold-silver bimetallic nanoclusters with bright red fluorescence as intracellular probes for imaging Hg2+ in living cells and zebrafish. The bimetallic nanoclusters of DTT-GSH@Au/AgNCs (DG-Au/AgNCs) with strong fluorescence that benefited from the synergistic effect of Au and Ag atoms were obtained through a one-pot synthesis method, incorporating glutathione (GSH) and dithiothreitol (DTT) as the reducers and functionalized ligands. Attractively, the bright red fluorescence of DG-Au/AgNCs could be rapidly and selectively quenched by Hg2+ within 1 min with a very low detection limit of 1.01 nM. Additionally, DG-Au/AgNCs had a great advantage in the detection of Hg2+ in living cells and zebrafish owing to its notably strong red fluorescence at 665 nm, which could avoid effectively auto-fluorescence interference from the organism. Such easily prepared bimetallic fluorescent nanoclusters would be expected to provide a noninvasive and sensitive approach in the detection of heavy metals in situ for environmental protection. |
| WOS关键词 | CARBON DOTS ; SENSITIVE DETECTION ; GOLD NANOCLUSTERS ; FLUORESCENT-PROBE ; HG2+ ; EMISSION ; SENSORS ; WATER ; RICH |
| 资助项目 | Key Research and Development Program of Zhejiang Province[2020C02024] ; Key Research and Development Program of Zhejiang Province[2021C02061] ; Public Projects of Zhejiang Province[LGC20C200004] ; National Natural Science Foundation of China[21806168] ; Natural Science Foundation of Anhui Province[2008085QB69] ; Scientific Research Foundation for High-Level Talents of West Anhui University[WGKQ2021001] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| 出版者 | SPRINGER HEIDELBERG |
| WOS记录号 | WOS:000784698600001 |
| 资助机构 | Key Research and Development Program of Zhejiang Province ; Public Projects of Zhejiang Province ; National Natural Science Foundation of China ; Natural Science Foundation of Anhui Province ; Scientific Research Foundation for High-Level Talents of West Anhui University |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/128461]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Yang, Linlin; Ye, Zihong |
| 作者单位 | 1.Chinese Acad Sci, Inst Solid State Phys, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China 2.West Anhui Univ, Sch Mat & Chem Engn, Key Lab Biomimet Sensor & Detecting Technol Anhui, Luan 237012, Anhui, Peoples R China 3.China Jiliang Univ, Coll Life Sci, Zhejiang Prov Key Lab Biometrol & Inspect & Quara, Hangzhou 310018, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jianping,Wang, Wang,Yang, Linlin,et al. Surface engineered bimetallic gold/silver nanoclusters for in situ imaging of mercury ions in living organisms[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2022. |
| APA | Wang, Jianping.,Wang, Wang.,Yang, Linlin.,Zhao, Jun.,Han, Guangmei.,...&Ye, Zihong.(2022).Surface engineered bimetallic gold/silver nanoclusters for in situ imaging of mercury ions in living organisms.ANALYTICAL AND BIOANALYTICAL CHEMISTRY. |
| MLA | Wang, Jianping,et al."Surface engineered bimetallic gold/silver nanoclusters for in situ imaging of mercury ions in living organisms".ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022). |
入库方式： OAI收割
来源：合肥物质科学研究院
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