Mechanisms of non-coding RNA-modulated alternative splicing in cancer
文献类型：期刊论文
| 作者 | Wang, Xiaolin2,3,4,5 ; Hua, Jinghan4,5; Li, Jingxin4; Zhang, Jiahui4,5; Dzakah, Emmanuel Enoch1; Cao, Guozhen4,5; Lin, Wenchu2,3,5
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| 刊名 | RNA BIOLOGY
 |
| 出版日期 | 2022-12-31 |
| 卷号 | 19 |
| ISSN号 | 1547-6286 |
| 关键词 | Alternative splicing splicing factor cancer progression miRNA lncRNA circRNA |
| DOI | 10.1080/15476286.2022.2062846 |
| 通讯作者 | Lin, Wenchu(wenchu@hmfl.ac.cn) |
| 英文摘要 | Alternative splicing (AS) is a common and pivotal process for eukaryotic gene expression regulation, which enables a precursor RNA to produce multiple transcript variants with diverse cellular functions. Aberrant AS represents a hallmark of cancer, engaged in all stages of tumorigenesis from initiation to metastasis. Accumulating pieces of evidence have revealed the involvement of non-coding RNAs (ncRNAs) in regulating AS in human cancers. In this review, we overview the underlying mechanisms of non-coding RNAs, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) modulated AS at diverse levels in human cancers, and summarize their regulatory functions in tumorigenesis. |
| WOS关键词 | CIRCULAR RNAS ; MESSENGER-RNA ; MYC ; IDENTIFICATION ; TRANSCRIPTION ; COMPLEXITY ; LANDSCAPE ; HALLMARKS ; INSIGHTS ; MALAT1 |
| 资助项目 | High Magnetic Field Laboratory of Anhui Province |
| WOS研究方向 | Biochemistry & Molecular Biology |
| 语种 | 英语 |
| 出版者 | TAYLOR & FRANCIS INC |
| WOS记录号 | WOS:000782921000001 |
| 资助机构 | High Magnetic Field Laboratory of Anhui Province |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/128665]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Lin, Wenchu |
| 作者单位 | 1.Univ Cape Coast, Coll Agr & Nat Sci, Sch Biol Sci, Dept Mol Biol & Biotechnol, Cape Coast, Ghana 2.High Magnet Field Lab Anhui Prov, Hefei, Anhui, Peoples R China 3.Chinese Acad Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, HIPS, Hefei, Anhui, Peoples R China 4.Univ Sci & Technol China, Hefei, Anhui, Peoples R China 5.Chinese Acad Sci, Hefei Inst Phys Sci Hips, High Magnet Field Lab, Hefei 230031, Anhui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xiaolin,Hua, Jinghan,Li, Jingxin,et al. Mechanisms of non-coding RNA-modulated alternative splicing in cancer[J]. RNA BIOLOGY,2022,19. |
| APA | Wang, Xiaolin.,Hua, Jinghan.,Li, Jingxin.,Zhang, Jiahui.,Dzakah, Emmanuel Enoch.,...&Lin, Wenchu.(2022).Mechanisms of non-coding RNA-modulated alternative splicing in cancer.RNA BIOLOGY,19. |
| MLA | Wang, Xiaolin,et al."Mechanisms of non-coding RNA-modulated alternative splicing in cancer".RNA BIOLOGY 19(2022). |
入库方式： OAI收割
来源：合肥物质科学研究院
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