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Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia

文献类型：期刊论文

作者Li, Ling15,16; Rami, Fatima Zahra15,16; Piao, Yan Hong15,16; Lee, Bo Mi15,16; Kim, Woo-Sung15,16; Sui, Jing11,12,13,14; Kim, Sung-Wan10; Lee, Bong Ju9; Kim, Jung Jin8; Yu, Je-Chun7
刊名EARLY INTERVENTION IN PSYCHIATRY
出版日期2022-02-06
页码10
ISSN号1751-7885
关键词clinical staging diagnostic stability outcome psychotic disorder NOS
DOI10.1111/eip.13276
通讯作者Chung, Young Chul(chungyc@jbnu.ac.kr)
英文摘要Aim: Research on psychotic disorder not otherwise specified (PNOS) that clearly mentions its subgroups is very rare. This study was conducted to identify the demographic and clinical features, cognitive function, and 1-year outcomes of patients with early stage PNOS compared with those with early stage schizophrenia (SZ). Methods: The study subjects were 54 and 321 patients with PNOS and SZ, respectively, who were registered at least more than 1 year ago. Due to drop out, only 37 and 210 patients with PNOS and SZ were evaluated at the 1-year follow-up. We compared clinical variables (duration of untreated psychosis, symptom severity, self-rating scales, and so on), cognitive function, and short-term outcomes (treatment response, remission, compliance, drop out, relapse) between the two groups. Results: The patients with PNOS were associated with higher diagnostic stability (53.7%) compared with those in previous studies. They had lower symptom severity, better treatment response at 2 months and higher remission rates at 12 months, but poorer compliance at 6 months compared with patients with SZ. Level of cognitive impairment in PNOS was intermediate between those of SZ patients and healthy controls. Conclusions: These findings indicate that PNOS has unique clinical features, suggesting that it should be treated as a distinct clinical syndrome. At the same time, however, prevention of its possible progression to other psychotic disorders in some patients with PNOS is also important.
WOS关键词DIAGNOSTIC STABILITY ; DSM-IV ; PSYCHOMETRIC PROPERTIES ; 1ST EPISODE ; DEPRESSION ; RECOVERY ; VALIDITY ; SCALES ; BIRTH
资助项目Korean Mental Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea[HL19C0015] ; Korea Health Industry Development Institute[HI18C2383]
WOS研究方向Psychiatry
语种英语
出版者WILEY
WOS记录号WOS:000751756700001
资助机构Korean Mental Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea ; Korea Health Industry Development Institute
源URL[http://ir.ia.ac.cn/handle/173211/47611]  
专题自动化研究所_脑网络组研究中心
通讯作者Chung, Young Chul
作者单位1.Seoul Natl Univ, Bundang Hosp, Dept Psychiat, Seongnam, South Korea
2.Natl Ctr Mental Hlth, Dept Social Psychiat & Rehabil, Seoul, South Korea
3.Korea Univ, Coll Med, Guro Hosp, Dept Psychiat, Seoul, South Korea
4.Inje Univ, Coll Med, Dept Psychiat, Goyang, South Korea
5.Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu, South Korea
6.Eulji Univ, Eulji Gen Hosp, Sch Med, Dept Psychiat, Seoul, South Korea
7.Eulji Univ, Eulji Univ Hosp, Sch Med, Dept Psychiat, Daejeon, South Korea
8.Catholic Univ Korea, Seoul St Marys Hosp, Dept Psychiat, Seoul, South Korea
9.Inje Univ, Haeundae Paik Hosp, Coll Med, Dept Psychiat, Busan, South Korea
10.Chonnam Natl Univ, Med Sch, Dept Psychiat, Gwangju, South Korea
推荐引用方式
GB/T 7714		 Li, Ling,Rami, Fatima Zahra,Piao, Yan Hong,et al. Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia[J]. EARLY INTERVENTION IN PSYCHIATRY,2022:10.
APA Li, Ling.,Rami, Fatima Zahra.,Piao, Yan Hong.,Lee, Bo Mi.,Kim, Woo-Sung.,...&Chung, Young Chul.(2022).Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia.EARLY INTERVENTION IN PSYCHIATRY,10.
MLA Li, Ling,et al."Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia".EARLY INTERVENTION IN PSYCHIATRY (2022):10.

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来源：自动化研究所

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