中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Cross-Phase Adversarial Domain Adaptation for Deep Disease-free Survival Prediction with Gastric Cancer CT Images

文献类型:会议论文

作者Wang Siwen1,2; Dong Di1,2; Li Hailin3; Feng Caizhen4; Wang Yi4; Tian Jie1,3
出版日期2021-12-09
会议日期Oct 31 - Nov 4, 2021
会议地点Mexico
英文摘要

Predicting gastric cancer disease-free survival (DFS) and identifying patients probably with high risk are imperative for more appropriate clinical treatment plans. Compared with CT-based radiomics researches adopting linear Cox proportional hazards models, deep neural networks can perform nonlinear transformations and investigate complex associations of image features with prognosis. Exploring shared information between post-contrast CT (with better visual enhancement) and pre-contrast CT (with few side effects and contraindications) is another challenge. In this work, a cross-phase adversarial domain adaptation (CPADA) framework is proposed to adapt a deep DFS prediction network (DDFS-Net) from arterial phase to pre-contrast phase. The DDFS-Net is designed for feature learning and trained by optimizing the average negative log function of Cox partial likelihood. The CPADA maps the feature space of pre-contrast phase (target) to arterial phase (source) in an adversarial manner by measuring Wasserstein distance. The proposed methods are evaluated on a dataset of 249 gastric cancer patients by concordance index, receiver operating characteristic curves, and Kaplan-Meier survival curves. The results demonstrate that our DDFS-Net outperforms linear survival analysis methods, and the CPADA works better than supervised learning and direct transfer schemes.

语种英语
源URL[http://ir.ia.ac.cn/handle/173211/48597]  
专题自动化研究所_中国科学院分子影像重点实验室
作者单位1.CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China
2.School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, 100049, China
3.Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beihang University, Beijing, 100191, China
4.Department of Radiology, Peking University People's Hospital, Beijing, 100044, China
推荐引用方式
GB/T 7714
Wang Siwen,Dong Di,Li Hailin,et al. Cross-Phase Adversarial Domain Adaptation for Deep Disease-free Survival Prediction with Gastric Cancer CT Images[C]. 见:. Mexico. Oct 31 - Nov 4, 2021.

入库方式: OAI收割

来源:自动化研究所

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