User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR)
文献类型：期刊论文
| 作者 | K. Wang; L. He; A. Manz and W. Wu |
| 刊名 | Analytical Chemistry
 |
| 出版日期 | 2021 |
| 卷号 | 93期号:3页码:1523-1528 |
| ISSN号 | 32700 |
| DOI | 10.1021/acs.analchem.0c03827 |
| 英文摘要 | One of the most important challenges in the field of microfluidics is the rapid fabrication of microchips with complex topologies. Although the processing method of microfluidic chips has made brilliant achievements in the past 20 years, almost all traditional processing methods still face huge obstacles in the production of complex topologies and three-dimensional microchannel. Nowadays, the main methods of manufacturing microfluidic chips such as numerical control microprocessing, laser ablation, inkjet printing, photolithography, dry etching, and lithography, galvanoformung and abformung (LIGA) technology are not only inapplicable to the complex topological structure and the rapid processing of three-dimensional microfluidic chips but also rely on expensive processing equipment, complex manufacturing process, and low yield. To solve the problems of these traditional processing methods, we propose a low-cost methodology to obtain a microfluidic chip by sewing the chip pipe to the substrate with an embroidery machine as low as $6. Compared with the above-mentioned traditional microprocessing technologies, the new chip processing technology proposed by us does not involve professional microprocessing equipment and professional skills. Therefore, this new chip processing technology can significantly improve the efficiency of microprocessing. 2020 American Chemical Society |
| URL标识 | 查看原文 |
| 源URL | [http://ir.ciomp.ac.cn/handle/181722/65738]  |
| 专题 | 中国科学院长春光学精密机械与物理研究所 |
| 推荐引用方式 GB/T 7714 | K. Wang,L. He,A. Manz and W. Wu. User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR)[J]. Analytical Chemistry,2021,93(3):1523-1528. |
| APA | K. Wang,L. He,&A. Manz and W. Wu.(2021).User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR).Analytical Chemistry,93(3),1523-1528. |
| MLA | K. Wang,et al."User-friendly microfabrication method for complex topological structure and three-dimensional microchannel with the application prospect in polymerase chain reaction (PCR)".Analytical Chemistry 93.3(2021):1523-1528. |
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