Cyber-Physical-Social Systems (CPSS) provides a novel perspective for constructing “Smart City”, which is also known as the Human-Machine-Things-System (HMTS), focusing on the fusion of ternary space: social network of human society, network of machines and the Internet of things. In this paper, we propose a specific implementation framework of CPSS for Smart City based on intelligent loops, including basic modeling and interactive fusion, state perception and cognition, and adaptive learning. On this basis, an overall architecture of the CPSS platform is designed, which is applied in the urban transportation management in Hangzhou. The application results demonstrate that the intelligent loop could optimize the control and management strategies for actual urban transportation.