Pregnane steroids from the twigs and leaves of Strophanthus divaricatus and their cytotoxic activities
文献类型:期刊论文
作者 | An, Pei-Pei1,2; Cui, Yong-Sheng1,2; Shi, Qiong-Yu2; Ren, Yu-Hao2; Wu, Pei-Qian1,2; Liu, Qun-Fang2; Liu, Hong-Chun2; Zhou, Bin2; Yue, Jian-Min1,2 |
刊名 | TETRAHEDRON LETTERS |
出版日期 | 2022-03-16 |
卷号 | 93页码:4 |
ISSN号 | 0040-4039 |
关键词 | Strophanthus divaricatus Pregnanes Structural elucidation Cytotoxic activity X-ray crystallography |
DOI | 10.1016/j.tetlet.2022.153691 |
通讯作者 | Zhou, Bin(zbbrush@simm.ac.cn) ; Yue, Jian-Min(jmyue@simm.ac.cn) |
英文摘要 | Four new pregnanes (1-4), including one 21-norpregnane (4), together with two known pregnanes (5 and 6), were isolated from the twigs and leaves of Strophanthus divaricatus. Their structures were elucidated on the basis of spectroscopic data analysis, ECD data, and X-ray crystallographic study. The cytotoxic activities of these pregnanes against two human cancer cell lines were evaluated. CO 2022 Elsevier Ltd. All rights reserved. |
资助项目 | National Natural Science Foundation[22177122] ; National Natural Science Foundation[22107106] ; Biological Resources Program, CAS of Peoples Republic of China[KFJ-BRP-008-001] ; Shanghai MunicipalScience and Technology Major Project |
WOS研究方向 | Chemistry |
语种 | 英语 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
WOS记录号 | WOS:000788864700004 |
源URL | [http://119.78.100.183/handle/2S10ELR8/299526] |
专题 | 新药研究国家重点实验室 |
通讯作者 | Zhou, Bin; Yue, Jian-Min |
作者单位 | 1.Nanjing Univ Chinese Med, Sch Chinese Mat Med, 138 Xianlin Rd, Nanjing 210023, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | An, Pei-Pei,Cui, Yong-Sheng,Shi, Qiong-Yu,et al. Pregnane steroids from the twigs and leaves of Strophanthus divaricatus and their cytotoxic activities[J]. TETRAHEDRON LETTERS,2022,93:4. |
APA | An, Pei-Pei.,Cui, Yong-Sheng.,Shi, Qiong-Yu.,Ren, Yu-Hao.,Wu, Pei-Qian.,...&Yue, Jian-Min.(2022).Pregnane steroids from the twigs and leaves of Strophanthus divaricatus and their cytotoxic activities.TETRAHEDRON LETTERS,93,4. |
MLA | An, Pei-Pei,et al."Pregnane steroids from the twigs and leaves of Strophanthus divaricatus and their cytotoxic activities".TETRAHEDRON LETTERS 93(2022):4. |
入库方式: OAI收割
来源:上海药物研究所
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