Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity
文献类型：期刊论文
| 作者 | Liu Yu2,3; You Yun-Xia2,3; Rao Li2,3; He Qian2,3; Su Yu2,3; Fan Yue2,3; Li Yi-Zhou2,3; Xu You-Kai1; Zhang Chuan-Rui2,3,4 |
| 刊名 | CHINESE JOURNAL OF NATURAL MEDICINES
 |
| 出版日期 | 2022-02-01 |
| 卷号 | 20期号:2页码:139-147 |
| 关键词 | Illicium micranthum Geranyl phenyl ethers Spectroscopic data Anti-HBV activity |
| ISSN号 | 2095-6975 |
| DOI | 10.1016/S1875-5364(21)60112-7 |
| 通讯作者 | Zhang Chuan-Rui(crzhang@cqu.edu.cn) |
| 英文摘要 | Fourteen new geranyl phenyl ethers (1-14) along with three known compounds (15-17) were isolated from Illicium micranthum, and their structures were elucidated by comprehensive spectroscopic methods. Illimicranins A-H (1-8) were characterized as geranyl vanillin ethers, while 9 and 10 were dimethyl acetal derivatives. Illimicranins I and J (11 and 12) were rare geranyl isoeugenol ethers. Illimicranins K and L (13 and 14) represented the first example of geranyl guaiacylacetone ether and geranyl zinger one ether, respectively. Compounds 1, 2 and 15 exhibited anti-HBV (hepatitis B virus) activity against HBsAg (hepatitis B surface antigen) and HBeAg (hepatitis B e antigen) secretion, and HBV DNA replication. |
| WOS关键词 | PRENYLATED C-6-C-3 COMPOUNDS ; SESQUITERPENE LACTONES ; STEM BARK ; ROOTS ; FRUITS ; NEOLIGNANS ; DITERPENES ; SIMONSII ; LIGNANS |
| 资助项目 | Chongqing Re-search and Frontier Technology[cstc2020jcyj-msxmX0537] ; State Key Laboratory of Drug Research[SIMM1903KF-14] ; Fun-damental Research Funds for the Central Universities[2020CDJ-LHZZ-006] |
| WOS研究方向 | Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000768386200006 |
| 出版者 | CHINESE JOURNAL NATURAL MEDICINES |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/300015]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Zhang Chuan-Rui |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Trop Plant Resource & Sustainable Use, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China 2.Chongqing Univ, Sch Pharmaceut Sci, Chongqing Key Lab Nat Prod Synth & Drug Res, Chongqing 401331, Peoples R China 3.Chongqing Univ, Sch Pharmaceut Sci, Chem Biol Res Ctr, Chongqing 401331, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu Yu,You Yun-Xia,Rao Li,et al. Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2022,20(2):139-147. |
| APA | Liu Yu.,You Yun-Xia.,Rao Li.,He Qian.,Su Yu.,...&Zhang Chuan-Rui.(2022).Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity.CHINESE JOURNAL OF NATURAL MEDICINES,20(2),139-147. |
| MLA | Liu Yu,et al."Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity".CHINESE JOURNAL OF NATURAL MEDICINES 20.2(2022):139-147. |
入库方式： OAI收割
来源：上海药物研究所
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