Advances and challenges in ginseng research from 2011 to 2020: the phytochemistry, quality control, metabolism, and biosynthesis
文献类型：期刊论文
| 作者 | Li, Xue2; Liu, Jie2; Zuo, Tian-tian2; Hu, Ying2; Li, Zheng2,3; Wang, Hong-da2; Xu, Xiao-yan2; Yang, Wen-zhi2; Guo, De-an1,2
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| 刊名 | NATURAL PRODUCT REPORTS
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| 出版日期 | 2022-02-07 |
| 页码 | 35 |
| ISSN号 | 0265-0568 |
| DOI | 10.1039/d1np00071c |
| 通讯作者 | Yang, Wen-zhi(wzyang0504@tjutcm.edu.cn) ; Guo, De-an(daguo@simm.ac.cn) |
| 英文摘要 | Covering: 2011 to the end of 2020 Panax species (Araliaceae), particularly P. ginseng, P. quinquefolius, and P. notoginseng, have a long history of medicinal use because of their remarkable tonifying effects, and currently serve as crucial sources for various healthcare products, functional foods, and cosmetics, aside from their vast clinical preparations. The huge market demand on a global scale prompts the continuous prosperity in ginseng research concerning the discovery of new compounds, precise quality control, ADME (absorption/disposition/metabolism/excretion), and biosynthesis pathways. Benefitting from the ongoing rapid development of analytical technologies, e.g. multi-dimensional chromatography (MDC), personalized mass spectrometry (MS) scan strategies, and multi-omics, highly recognized progress has been made in driving ginseng analysis towards "systematicness, integrity, personalization, and intelligentization". Herein, we review the advances in the phytochemistry, quality control, metabolism, and biosynthesis pathway of ginseng over the past decade (2011-2020), with 410 citations. Emphasis is placed on the introduction of new compounds isolated (saponins and polysaccharides), and the emerging novel analytical technologies and analytical strategies that favor ginseng's authentic use and global consumption. Perspectives on the challenges and future trends in ginseng analysis are also presented. |
| WOS关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY ; PANAX-NOTOGINSENG-SAPONINS ; TANDEM MASS-SPECTROMETRY ; DAMMARANE-TYPE SAPONINS ; NONTARGETED METABOLOMICS APPROACH ; LINEAR ION-TRAP ; Q-TOF-MS/MS ; MICROBIOTA-MEDIATED BIOTRANSFORMATION ; NATURAL COMPOUNDS CHARACTERIZATION ; HUMAN INTESTINAL MICROFLORA |
| 资助项目 | National Natural Science Foundation of China[81872996] ; National Natural Science Foundation of China[8213000165] ; Natural Science Foundation of Tianjin of China[20JCYBJC00060] ; Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine[ZYYCXTD-D-202002] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000751921700001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/300135]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Yang, Wen-zhi; Guo, De-an |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai Inst Mat Med, Natl Engn Lab TCM Standardizat Technol, 501 Haike Rd, Shanghai 201203, Peoples R China 2.Tianjin Univ Tradit Chinese Med, State Key Lab Component Based Chinese Med, Tianjin Key Lab TCM Chem & Anal, 10 Poyanghu Rd, Tianjin 301617, Peoples R China 3.Tianjin Univ Tradit Chinese Med, Coll Pharmaceut Engn Tradit Chinese Med, Tianjin 301617, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xue,Liu, Jie,Zuo, Tian-tian,et al. Advances and challenges in ginseng research from 2011 to 2020: the phytochemistry, quality control, metabolism, and biosynthesis[J]. NATURAL PRODUCT REPORTS,2022:35. |
| APA | Li, Xue.,Liu, Jie.,Zuo, Tian-tian.,Hu, Ying.,Li, Zheng.,...&Guo, De-an.(2022).Advances and challenges in ginseng research from 2011 to 2020: the phytochemistry, quality control, metabolism, and biosynthesis.NATURAL PRODUCT REPORTS,35. |
| MLA | Li, Xue,et al."Advances and challenges in ginseng research from 2011 to 2020: the phytochemistry, quality control, metabolism, and biosynthesis".NATURAL PRODUCT REPORTS (2022):35. |
入库方式： OAI收割
来源：上海药物研究所
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