p Anticancer Effects of Ginsenoside Rh2: A Systematic Review
文献类型：期刊论文
| 作者 | He, Xin-Ling2; Xu, Xiao-Huang2; Shi, Jia-Jie2; Huang, Mingqing1; Wang, Yitao2; Chen, Xiuping2; Lu, Jin-Jian2,3 |
| 刊名 | CURRENT MOLECULAR PHARMACOLOGY
 |
| 出版日期 | 2022 |
| 卷号 | 15期号:1页码:179-189 |
| 关键词 | Ginseng ginsenoside Rh2 cancer cytotoxicity mechanism natural compound |
| ISSN号 | 1874-4672 |
| DOI | 10.2174/1874467214666210309115105 |
| 通讯作者 | Lu, Jin-Jian(jinjianlu@um.edu.mo) |
| 英文摘要 | Background: As one of the effective pharmacological constituents of Ginseng Radix et Rhizoma, ginsenoside Rh2 (Rh2) exerts a remarkable anticancer effect on various cancer cell lines in vitro and strongly inhibits tumor growth in vivo without severe toxicity. Objective: This article reviewed existing evidence supporting the anticancer effects of Rh2 to classify and conclude previous and current knowledge on the mechanisms and therapeutic effects of Rh2, as well as to promote the clinical application of this natural product. |
| WOS关键词 | HUMAN LEUKEMIA-CELLS ; IN-VITRO ; 20(S)-GINSENOSIDE RH2 ; PANAX-GINSENG ; DEPENDENT INHIBITION ; JAK2/STAT3 PATHWAY ; IMMUNE-RESPONSES ; PROSTATE-CANCER ; CARCINOMA CELLS ; CYCLE ARREST |
| 资助项目 | National Natural Science Foundation of China[81973516] ; University of Ma-cau[CPG2021-00022-ICMS] ; State Key Labora-tory of Drug Research[SIMM2004KF-05] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000745544300011 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/300159]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Lu, Jin-Jian |
| 作者单位 | 1.Fujian Univ Tradit Chinese Med, Coll Pharm, Fuzhou 350122, Peoples R China 2.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Xin-Ling,Xu, Xiao-Huang,Shi, Jia-Jie,et al. p Anticancer Effects of Ginsenoside Rh2: A Systematic Review[J]. CURRENT MOLECULAR PHARMACOLOGY,2022,15(1):179-189. |
| APA | He, Xin-Ling.,Xu, Xiao-Huang.,Shi, Jia-Jie.,Huang, Mingqing.,Wang, Yitao.,...&Lu, Jin-Jian.(2022).p Anticancer Effects of Ginsenoside Rh2: A Systematic Review.CURRENT MOLECULAR PHARMACOLOGY,15(1),179-189. |
| MLA | He, Xin-Ling,et al."p Anticancer Effects of Ginsenoside Rh2: A Systematic Review".CURRENT MOLECULAR PHARMACOLOGY 15.1(2022):179-189. |
入库方式： OAI收割
来源：上海药物研究所
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