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Palladium-catalyzed diarylative dearomatization of indoles with aryl thioesters

文献类型：期刊论文

作者Huang, Wei1; Han, Ming-Liang4,5; Liu, Yu-Wen2,3; Xu, Hui2; Dai, Hui-Xiong2,3
刊名CHINESE CHEMICAL LETTERS
出版日期2021-09-01
卷号32期号:9页码:2765-2768
关键词Thioester Decarbonylation Dearomatization Indolines skeleton Diarylation
ISSN号1001-8417
DOI10.1016/j.cclet.2021.02.048
通讯作者Xu, Hui(xuhui2018@simm.ac.cn) ; Dai, Hui-Xiong(hxdai@simm.ac.cn)
英文摘要We report herein a palladium-catalyzed diarylative dearomatization of indole by employing thioester and arylboronic acid as the aryl electrophiles. The reaction involved a decarbonylation/migratory insertion/terminal Suzuki coupling procedure. Substrates bearing various functional groups are well tolerated in the reaction, affording the diarylated indoline skeletons in moderate to good yields. (C) 2021 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
WOS关键词THIOL ESTERS ; BOND FORMATION ; EFFICIENT ; DECARBONYLATION ; REDUCTION ; ALKALOIDS ; ALDEHYDES ; CLEAVAGE
资助项目Shanghai Institute of Materia Medica ; Chinese Academy of Sciences ; National Natural Science Foundation of China[21772211] ; National Natural Science Foundation of China[21920102003] ; Youth Innovation Promotion Association CAS[2014229] ; Youth Innovation Promotion Association CAS[2018293] ; Science and Technology Commission of Shanghai Municipality[17JC1405000] ; Science and Technology Commission of Shanghai Municipality[18431907100] ; Program of Shanghai Academic Research Leader[19XD1424600] ; National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China[2018ZX09711002-006]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000735948800001
出版者ELSEVIER SCIENCE INC
源URL[http://119.78.100.183/handle/2S10ELR8/300649]  
专题中国科学院上海药物研究所
通讯作者Xu, Hui; Dai, Hui-Xiong
作者单位1.Nanchang Univ, Sch Pharm, Nanchang 330006, Jiangxi, Peoples R China
2.Chinese Acad Sci, Key Lab Receptor Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Shenzhen Univ, Inst Adv Study, Shenzhen 518060, Peoples R China
5.Shenzhen Univ, Coll Optoelect Engn, Key Lab Optoelect Devices & Syst, Minist Educ & Guangdong Prov, Shenzhen 518060, Peoples R China
推荐引用方式
GB/T 7714		 Huang, Wei,Han, Ming-Liang,Liu, Yu-Wen,et al. Palladium-catalyzed diarylative dearomatization of indoles with aryl thioesters[J]. CHINESE CHEMICAL LETTERS,2021,32(9):2765-2768.
APA Huang, Wei,Han, Ming-Liang,Liu, Yu-Wen,Xu, Hui,&Dai, Hui-Xiong.(2021).Palladium-catalyzed diarylative dearomatization of indoles with aryl thioesters.CHINESE CHEMICAL LETTERS,32(9),2765-2768.
MLA Huang, Wei,et al."Palladium-catalyzed diarylative dearomatization of indoles with aryl thioesters".CHINESE CHEMICAL LETTERS 32.9(2021):2765-2768.

入库方式： OAI收割

来源：上海药物研究所

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