Anti-ageing peptides and proteins for topical applications: a review
文献类型:期刊论文
作者 | Liu, Mengyang2; Chen, Shuo2; Zhang, Zhiwen3; Li, Hongyu1; Sun, Guiju4; Yin, Naibo2; Wen, Jingyuan2 |
刊名 | PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY |
出版日期 | 2022-01-06 |
页码 | 18 |
ISSN号 | 1083-7450 |
关键词 | Anti-ageing proteins and peptides antioxidants dermal delivery nanoparticulate drug delivery systems semi-solid dosage forms |
DOI | 10.1080/10837450.2021.2023569 |
通讯作者 | Wen, Jingyuan(j.wen@auckland.ac.nz) |
英文摘要 | Skin ageing is a cumulative result of oxidative stress, predominantly caused by reactive oxygen species (ROS). Respiration, pollutants, toxins, or ultraviolet A (UVA) irradiation produce ROS with 80% of skin damage attributed to UVA irradiation. Anti-ageing peptides and proteins are considered valuable compounds for removing ROS to prevent skin ageing and maintenance of skin health. In this review, skin ageing theory has been illustrated with a focus on the mechanism and relationship with anti-ageing peptides and proteins. The effects, classification, and transport pathways of anti-ageing peptides and proteins across skin are summarized and discussed. Over the last decade, several novel formulations and advanced strategies have been developed to overcome the challenges in the dermal delivery of proteins and peptides for skin ageing. This article also provides an in-depth review of the latest advancements in the dermal delivery of anti-ageing proteins and peptides. Based on these studies, this review prospected several semi-solid dosage forms to achieve topical applicability for anti-ageing peptides and proteins. |
WOS关键词 | DRUG-DELIVERY ; STRATUM-CORNEUM ; LIPID OXIDATION ; IN-VITRO ; BIOMEDICAL APPLICATIONS ; PENETRATION ENHANCERS ; TRANSDERMAL DELIVERY ; BARRIER PROPERTIES ; SKIN PENETRATION ; ACID |
WOS研究方向 | Pharmacology & Pharmacy |
语种 | 英语 |
出版者 | TAYLOR & FRANCIS LTD |
WOS记录号 | WOS:000739719600001 |
源URL | [http://119.78.100.183/handle/2S10ELR8/300697] |
专题 | 中国科学院上海药物研究所 |
通讯作者 | Wen, Jingyuan |
作者单位 | 1.Univ Arkansas Med Sci, Sch Pharm, Little Rock, AR 72205 USA 2.Univ Auckland, Fac Med & Hlth Sci, Sch Pharm, Auckland, New Zealand 3.Chinese Acad Sci, Shanghai Inst Mat Med, Beijing, Peoples R China 4.Southeast Univ, Sch Publ Hlth, Dept Nutr & Food Hyg, Nanjing, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Mengyang,Chen, Shuo,Zhang, Zhiwen,et al. Anti-ageing peptides and proteins for topical applications: a review[J]. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY,2022:18. |
APA | Liu, Mengyang.,Chen, Shuo.,Zhang, Zhiwen.,Li, Hongyu.,Sun, Guiju.,...&Wen, Jingyuan.(2022).Anti-ageing peptides and proteins for topical applications: a review.PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY,18. |
MLA | Liu, Mengyang,et al."Anti-ageing peptides and proteins for topical applications: a review".PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2022):18. |
入库方式: OAI收割
来源:上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。