Supramolecular cancer photoimmunotherapy based on precise peptide self-assembly design
文献类型：期刊论文
| 作者 | Liu, Yamei1; Zhang, Lu2; Chang, Rui1; Yan, Xuehai1,3,4 |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2022-02-15 |
| 卷号 | 58期号:14页码:2247-2258 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/d1cc06355c |
| 英文摘要 | Combinational photoimmunotherapy (PIT) is considered to be an ideal strategy for the treatment of highly recurrent and metastatic cancer, because it can ablate the primary tumor and provide in situ an autologous tumor vaccine to induce the host immune response, ultimately achieving the goal of controlling tumor growth and distal metastasis. Significant efforts have been devoted to enhancing the immune response caused by phototherapy-eliminated tumors. Recently, supramolecular PIT nanoagents based on precise peptide self-assembly design have been employed to improve the efficacy of photoimmunotherapy by utilizing the stability, targeting capability and flexibility of drugs, increasing tumor immunogenicity and realizing the synergistic amplification of immune effects through multiple pathways and collaborative strategy. This review summarizes peptide-based supramolecular PIT nanoagents for phototherapy-synergized cancer immunotherapy and its progress in enhancing the effect of photoimmunotherapy, especially focusing on the design of peptide-based PIT nanoagents, the progress of bioactive peptides combined photoimmunotherapy, and the synergistic immune-response mechanism. |
| WOS关键词 | IMMUNOTHERAPY ; METASTASIS ; HYDROGELS |
| 资助项目 | National Natural Science Foundation of China[22102188] ; National Natural Science Foundation of China[22025207] ; Innovation Research Community Science Fund of China[21821005] ; National Natural Science Fund BRICS STI Framework Programme[51861145304] ; Chinese Postdoctoral Science Foundation[2020M680674] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000749719600001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 资助机构 | National Natural Science Foundation of China ; Innovation Research Community Science Fund of China ; National Natural Science Fund BRICS STI Framework Programme ; Chinese Postdoctoral Science Foundation |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/51886]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Yan, Xuehai |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 3.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Ctr Mesosci, Inst Proc Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Yamei,Zhang, Lu,Chang, Rui,et al. Supramolecular cancer photoimmunotherapy based on precise peptide self-assembly design[J]. CHEMICAL COMMUNICATIONS,2022,58(14):2247-2258. |
| APA | Liu, Yamei,Zhang, Lu,Chang, Rui,&Yan, Xuehai.(2022).Supramolecular cancer photoimmunotherapy based on precise peptide self-assembly design.CHEMICAL COMMUNICATIONS,58(14),2247-2258. |
| MLA | Liu, Yamei,et al."Supramolecular cancer photoimmunotherapy based on precise peptide self-assembly design".CHEMICAL COMMUNICATIONS 58.14(2022):2247-2258. |
入库方式： OAI收割
来源：过程工程研究所
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